Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 14/20 | 0.41 |
| ▸ | CA12 | O43570 | 12/20 | 0.41 |
| ▸ | CA9 | Q16790 | 12/20 | 0.41 |
| ▸ | CA7 | P43166 | 4/20 | 0.41 |
| ▸ | CA1 | P00915 | 12/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.33 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.33 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 3/20 | 0.33 |
| ▸ | CA6 | P23280 | 3/20 | 0.33 |
| ▸ | CA5A | P35218 | 2/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CA3 | P07451 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30772256 | 0.79 | GAA (0.51) | BRD4SMARCA2SMARCA4PBRM1GAA | |
| SCHEMBL27195862 | 0.79 | GAA (0.51) | BRD4SMARCA2SMARCA4PBRM1GAA | |
| SCHEMBL25809466 | 0.77 | CA2 (0.47) | CA2CA12CA9CA7CA1 | |
| SCHEMBL20129650 | 0.74 | CA2 (0.43) | CA2CA12CA9CA7CA1 | |
| SCHEMBL31321262 | 0.74 | KMT2A (0.51) | HSD11B1ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL8261936 | 0.73 | GAA (0.58) | CA2CA12CA9CA7CA1 | |
| SCHEMBL17897242 | 0.72 | KDM4E (0.41) | DRD2ALDH1A1SMN1; SMN2 | |
| SCHEMBL17897247 | 0.72 | KDM4E (0.41) | DRD2ALDH1A1SMN1; SMN2 | |
| SCHEMBL19003675 | 0.72 | KDM4E (0.41) | DRD2ALDH1A1SMN1; SMN2 | |
| SCHEMBL4059759 | 0.70 | CA2 (0.50) | CA2CA12CA9CA7CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |