Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.36 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.36 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | DHFR | P00374 | 2/20 | 0.33 |
| ▸ | MC4R | P32245 | 1/20 | 0.32 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.31 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20157486 | 0.79 | CA2 (0.41) | GAABRD4SMARCA2SMARCA4PBRM1 | |
| SCHEMBL19003675 | 0.78 | KDM4E (0.41) | MEN1KMT2AADRA2CKDM4ESMN1; SMN2 | |
| SCHEMBL17897242 | 0.78 | KDM4E (0.41) | MEN1KMT2AADRA2CKDM4ESMN1; SMN2 | |
| SCHEMBL17897247 | 0.78 | KDM4E (0.41) | MEN1KMT2AADRA2CKDM4ESMN1; SMN2 | |
| SCHEMBL18040067 | 0.77 | GAA (0.56) | GAAMEN1USP2KMT2AADRA2C | |
| SCHEMBL31321262 | 0.76 | KMT2A (0.51) | GAAMEN1KMT2AKDM4EHTT | |
| SCHEMBL23152040 | 0.72 | ADRA2C (0.79) | GAAMEN1USP2KMT2AADRA2C | |
| SCHEMBL11775877 | 0.72 | ADRA2C (0.79) | GAAMEN1USP2KMT2AADRA2C | |
| SCHEMBL17897231 | 0.72 | GRM1 (0.52) | KDM4EGRM1 | |
| SCHEMBL3076827 | 0.70 | GAA (0.65) | GAAMEN1USP2KMT2AADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117561238-A | Phenylurea derivatives | 住友制药株式会社 | 2024-02-13 | — | — | CN | disclosed |