Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | PTPRC | P08575 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | GABRP | O00591 | 1/20 | 0.32 |
| ▸ | GABRD | O14764 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21362517 | 0.88 | BRD4 (0.40) | BRD4PTPRCKMT2AKDM4EP2RX3 | |
| SCHEMBL21362150 | 0.88 | BRD4 (0.40) | BRD4PTPRCKMT2AKDM4EP2RX3 | |
| SCHEMBL21362518 | 0.87 | BRD4 (0.45) | BRD4PTPRCKMT2AKDM4EP2RX3 | |
| SCHEMBL21362563 | 0.77 | BRD4 (0.53) | BRD4KMT2AKDM4EP2RX3MAPT | |
| SCHEMBL21362113 | 0.76 | PTPRC (0.30) | PTPRC | |
| SCHEMBL21362114 | 0.76 | PTPRC (0.30) | PTPRC | |
| SCHEMBL20157810 | 0.76 | BRD4 (0.46) | BRD4KMT2AKDM4EPPARGPPARA | |
| SCHEMBL21362559 | 0.76 | BRD4 (0.52) | BRD4KMT2AKDM4EP2RX3MAPT | |
| SCHEMBL21362149 | 0.76 | BRD4 (0.40) | BRD4KMT2AKDM4EP2RX3ALDH1A1 | |
| SCHEMBL21352026 | 0.75 | BRD4 (0.48) | BRD4KMT2AKDM4EP2RX3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018086605-A1 | NITROGENOUS MACROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION AND APPLICATION THEREOF | 山东罗欣药业集团股份有限公司 | 2018-05-17 | — | — | WO | disclosed |