Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | PTPRC | P08575 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | PPARA | Q07869 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21362150 | 1.00 | BRD4 (0.40) | BRD4PTPRCKMT2ACNR2KDM4E | |
| SCHEMBL21362113 | 0.89 | PTPRC (0.30) | PTPRC | |
| SCHEMBL21362114 | 0.89 | PTPRC (0.30) | PTPRC | |
| SCHEMBL20157788 | 0.88 | BRD4 (0.43) | BRD4PTPRCKMT2AKDM4EP2RX3 | |
| SCHEMBL21362149 | 0.87 | BRD4 (0.40) | BRD4KMT2ACNR2KDM4EP2RX3 | |
| SCHEMBL21362103 | 0.85 | BRD4 (0.46) | BRD4KMT2ACNR2KDM4EP2RX3 | |
| SCHEMBL21362518 | 0.83 | BRD4 (0.45) | BRD4PTPRCKMT2AKDM4EP2RX3 | |
| SCHEMBL21362230 | 0.80 | BRD4 (0.39) | BRD4 | |
| SCHEMBL21362229 | 0.80 | BRD4 (0.39) | BRD4 | |
| SCHEMBL9280622 | 0.77 | BRD4 (0.37) | BRD4PTPRCKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3539960-A1 | NITROGENOUS MACROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION AND APPLICATION THEREOF | Luoxin Pharmaceutical (Shanghai) Co., Ltd. (CN) | 2019-09-18 | — | — | EP | disclosed |