SCHEMBL20157798

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10599055	0.86	SRD5A2 (0.54)	MAPTCES2CES1NPC1MAPK1
	SCHEMBL20157816	0.85	MAPT (0.51)	MAPTNPC1MAPK1HTTKMT2A
	SCHEMBL10877792	0.84	FLT1 (0.55)	MAPTCES2CES1NPC1MAPK1
	SCHEMBL20157547	0.83	MAPT (0.50)	MAPTNPC1MAPK1HTTKMT2A
	SCHEMBL7213795	0.83	MAPT (0.53)	MAPTCES2CES1NPC1MAPK1
	SCHEMBL30882570	0.83	MAPT (0.53)	MAPTCES2CES1NPC1MAPK1
	SCHEMBL7271917	0.83	SRD5A2 (0.60)	MAPTCES2CES1NPC1MAPK1
	SCHEMBL21550127	0.82	SMN1; SMN2 (0.50)	MAPTNPC1MAPK1HTTKMT2A
	SCHEMBL27774516	0.82	MAPT (0.44)	MAPTNPC1MAPK1HTTKMT2A
	SCHEMBL9002496	0.81	MEN1 (0.56)	MAPTCES2CES1NPC1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.