Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30882570 | 1.00 | MAPT (0.53) | MAPTNPC1MAPK1HTTPOLB | |
| SCHEMBL27774516 | 0.85 | MAPT (0.44) | MAPTNPC1MAPK1HTTGAA | |
| SCHEMBL20157816 | 0.84 | MAPT (0.51) | MAPTNPC1MAPK1HTTPOLB | |
| SCHEMBL28384878 | 0.83 | AKR1C3 (0.61) | MAPTNPC1MAPK1HTTPOLB | |
| SCHEMBL20157798 | 0.83 | MAPT (0.50) | MAPTNPC1MAPK1HTTPOLB | |
| SCHEMBL20157547 | 0.83 | MAPT (0.50) | MAPTNPC1MAPK1HTTAKR1C3 | |
| SCHEMBL20157966 | 0.83 | LMNA (0.49) | MAPTNPC1MAPK1HTTPOLB | |
| SCHEMBL9267999 | 0.81 | MAPT (0.66) | MAPTMAPK1HTTPOLBAKR1C3 | |
| SCHEMBL29380078 | 0.81 | AKR1C3 (0.59) | MAPTNPC1MAPK1HTTPOLB | |
| SCHEMBL29530940 | 0.81 | MAPT (0.66) | MAPTMAPK1HTTPOLBAKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116332828-A | Dibenzocycloheptanone derivatives and application thereof in OLED (organic light emitting diode) device | 四川大学 | 2023-06-27 | — | — | CN | disclosed |
| EP-1208571-B1 | CABLE, IN PARTICULAR FOR TRANSPORT OR DISTRIBUTION OF ELECTRICAL ENERGY AND INSULATING COMPOSITION | PIRELLI (IT) | 2003-10-01 | — | — | EP | disclosed |
| US-20020164480-A1 | Cable, in particular for transport or distribution of electrical energy and insulating composition | PRYSMIAN CAVI E SISTEMI ENERGIA S.R.L. (IT) | 2002-11-07 | — | — | US | disclosed |
| EP-1208571-A1 | CABLE, IN PARTICULAR FOR TRANSPORT OR DISTRIBUTION OF ELECTRICAL ENERGY AND INSULATING COMPOSITION | PIRELLI CAVI E SISTEMI S.p.A. (IT) | 2002-05-29 | — | — | EP | disclosed |
| WO-2001008166-A1 | CABLE, IN PARTICULAR FOR TRANSPORT OR DISTRIBUTION OF ELECTRICAL ENERGY AND INSULATING COMPOSITION | PIRELLI CAVI E SISTEMI S.P.A. (IT) | 2001-02-01 | — | — | WO | disclosed |