SCHEMBL20157547

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	Sulfamide SCHEMBL21352062	0.93	MAPT (0.48)	MAPTHTTNPC1MAPK1F2
	SCHEMBL20157554	0.87	MAPT (0.54)	MAPTHTTNPC1MAPK1F2
	SCHEMBL11860220	0.86	LTA4H (0.46)	MAPTNPC1MAPK1LMNAALDH1A1
	SCHEMBL20157816	0.85	MAPT (0.51)	MAPTHTTNPC1MAPK1LMNA
	SCHEMBL1584825	0.84	F2 (0.59)	MAPTHTTNPC1MAPK1F2
	SCHEMBL20157798	0.83	MAPT (0.50)	MAPTHTTNPC1MAPK1LMNA
	SCHEMBL14099187	0.83	LMNA (0.50)	MAPTHTTNPC1MAPK1F2
	SCHEMBL7213795	0.83	MAPT (0.53)	MAPTHTTNPC1MAPK1SMN1; SMN2
	SCHEMBL30882570	0.83	MAPT (0.53)	MAPTHTTNPC1MAPK1SMN1; SMN2
	SCHEMBL20157894	0.82	CES2 (0.50)	HTTLMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.