Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 9/20 | 0.35 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.32 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.32 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.32 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21564816 | 0.92 | ALDH2 (0.35) | BRD4BAZ2BBAZ2A | |
| SCHEMBL21564957 | 0.85 | ALDH2 (0.36) | BRD4BAZ2BBAZ2A | |
| SCHEMBL21564968 | 0.84 | MAP2K2 (0.32) | BRD4MAP2K2MAP2K1BAZ2BBAZ2A | |
| SCHEMBL28468872 | 0.83 | BRD4 (0.40) | BRD4 | |
| SCHEMBL21362118 | 0.80 | BRD4 (0.42) | BRD4MAP2K2MAP2K1BAZ2BBAZ2A | |
| SCHEMBL28470558 | 0.80 | BRD4 (0.34) | BRD4 | |
| SCHEMBL20157930 | 0.80 | BRD4 (0.37) | BRD4MAP2K2MAP2K1 | |
| SCHEMBL21550002 | 0.78 | ALDH2 (0.34) | BRD4BAZ2BBAZ2A | |
| SCHEMBL21550003 | 0.78 | ALDH2 (0.34) | BRD4BAZ2BBAZ2A | |
| SCHEMBL21564831 | 0.77 | P2RX7 (0.34) | BRD4MAP2K2MAP2K1BAZ2BBAZ2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019214399-A1 | BENZO- SEVEN-MEMBERED HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF, AND APPLICATION THEREOF | 罗欣药业(上海)有限公司 (CN) | 2019-11-14 | — | — | WO | disclosed |