Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.63 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.63 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MPO | P05164 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.48 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22201589 | 0.87 | IRAK4 (0.54) | KDM4DKDM4CIRAK4GAARAB9A | |
| SCHEMBL9979195 | 0.81 | KDM4D (0.56) | KDM4DKDM4CIRAK4GAACYP1A2 | |
| SCHEMBL23463919 | 0.80 | HDAC1 (0.56) | KDM4DKDM4CGAARAB9AKDM4E | |
| SCHEMBL18422044 | 0.80 | IRAK4 (0.50) | KDM4DKDM4CIRAK4GAAKDM4E | |
| SCHEMBL29601833 | 0.80 | IRAK4 (0.50) | KDM4DKDM4CIRAK4GAAKDM4E | |
| SCHEMBL29892972 | 0.79 | KDM4C (0.52) | KDM4DKDM4CIRAK4KDM4ECA1 | |
| SCHEMBL4934772 | 0.79 | IRAK4 (0.49) | KDM4DKDM4CIRAK4KDM4ESIRT2 | |
| SCHEMBL259608 | 0.78 | ALDH1A1 (0.61) | KDM4DKDM4CRAB9AKMT2ANPSR1 | |
| SCHEMBL17711000 | 0.77 | KDM4C (0.51) | KDM4DKDM4CIRAK4KDM4EHTT | |
| SCHEMBL18421265 | 0.77 | KDM4C (0.51) | KDM4DKDM4CIRAK4KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011072873-A1 | SPECIFIC SORBENT FOR BINDING PROTEINS AND PEPTIDES, AND SEPARATION METHOD USING THE SAME | INSTRACTION GMBH (DE) | 2011-06-23 | — | — | WO | claimed |
| WO-2011072873-A1 | SPECIFIC SORBENT FOR BINDING PROTEINS AND PEPTIDES, AND SEPARATION METHOD USING THE SAME | INSTRACTION GMBH (DE) | 2011-06-23 | — | — | WO | disclosed |