Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 20/20 | 0.69 |
| ▸ | ITGAV | P06756 | 20/20 | 0.69 |
| ▸ | ITGB5 | P18084 | 20/20 | 0.69 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20158271 | 0.86 | ITGAV (0.57) | ITGB3ITGAVITGB5ITGB1 | |
| SCHEMBL20142183 | 0.86 | ITGB3 (0.62) | ITGB3ITGAVITGB5ITGB1 | |
| SCHEMBL20142177 | 0.86 | ITGB3 (0.62) | ITGB3ITGAVITGB5ITGB1 | |
| SCHEMBL20142503 | 0.85 | ITGB3 (0.62) | ITGB3ITGAVITGB5ITGB1 | |
| SCHEMBL20142506 | 0.85 | ITGB3 (0.62) | ITGB3ITGAVITGB5ITGB1 | |
| SCHEMBL20158092 | 0.85 | ITGB3 (0.67) | ITGB3ITGAVITGB5ITGB1 | |
| SCHEMBL21314582 | 0.85 | ITGB3 (0.67) | ITGB3ITGAVITGB5ITGB1 | |
| SCHEMBL29701355 | 0.85 | ITGB3 (0.67) | ITGB3ITGAVITGB5ITGB1 | |
| SCHEMBL20158340 | 0.83 | ITGB3 (0.63) | ITGB3ITGAVITGB5ITGB1 | |
| SCHEMBL20141606 | 0.82 | ITGB3 (0.63) | ITGB3ITGAVITGB5ITGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089355-A1 | CYCLOBUTANE- AND AZETIDINE-CONTAINING MONO AND SPIROCYCLIC COMPOUNDS AS ALPHA V INTEGRIN INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-05-17 | — | — | WO | disclosed |