Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAV | P06756 | 20/20 | 0.57 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.57 |
| ▸ | ITGB5 | P18084 | 4/20 | 0.57 |
| ▸ | ITGB6 | P18564 | 16/20 | 0.57 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20158072 | 0.86 | ITGB3 (0.69) | ITGAVITGB3ITGB5ITGB1 | |
| SCHEMBL29701350 | 0.84 | ITGB3 (0.60) | ITGAVITGB3ITGB5ITGB6 | |
| SCHEMBL21314354 | 0.84 | ITGB3 (0.60) | ITGAVITGB3ITGB5ITGB6 | |
| SCHEMBL21317539 | 0.84 | ITGB3 (0.60) | ITGAVITGB3ITGB5ITGB6 | |
| SCHEMBL21317466 | 0.84 | ITGB3 (0.60) | ITGAVITGB3ITGB5ITGB6 | |
| SCHEMBL21314342 | 0.84 | ITGB3 (0.60) | ITGAVITGB3ITGB5ITGB6 | |
| SCHEMBL21314351 | 0.84 | ITGAV (0.61) | ITGAVITGB3ITGB5ITGB6 | |
| SCHEMBL21317480 | 0.84 | ITGAV (0.61) | ITGAVITGB3ITGB5ITGB6 | |
| SCHEMBL21314407 | 0.84 | ITGAV (0.69) | ITGAVITGB3ITGB5ITGB6 | |
| SCHEMBL21317483 | 0.84 | ITGAV (0.69) | ITGAVITGB3ITGB5ITGB6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089355-A1 | CYCLOBUTANE- AND AZETIDINE-CONTAINING MONO AND SPIROCYCLIC COMPOUNDS AS ALPHA V INTEGRIN INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-05-17 | — | — | WO | disclosed |