Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.46 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.46 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.43 |
| ▸ | GABRP | O00591 | 1/20 | 0.43 |
| ▸ | GABRD | O14764 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.43 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.43 |
| ▸ | GABRR2 | P28476 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16360052 | 0.88 | LMNA (0.53) | LMNASLC22A6TSHRNFKB1PMP22 | |
| SCHEMBL8764112 | 0.84 | LMNA (0.48) | LMNASLC22A6TSHRNFKB1PMP22 | |
| SCHEMBL13657827 | 0.83 | TSHR (0.67) | LMNASLC22A6TSHRNFKB1PMP22 | |
| SCHEMBL20240413 | 0.82 | AKR1B1 (0.48) | LMNASLC22A6TSHRNFKB1PMP22 | |
| Ethylenediamine SCHEMBL8323802 | 0.82 | LMNA (0.58) | LMNASLC22A6TSHRNFKB1PMP22 | |
| SCHEMBL11577981 | 0.80 | AKR1B1 (0.58) | SLC22A6TSHRKMT2AHDAC11GPR84 | |
| SCHEMBL24570655 | 0.79 | — | — | |
| SCHEMBL7389117 | 0.78 | LMNA (0.53) | LMNASLC22A6TSHRNFKB1PMP22 | |
| SCHEMBL112741 | 0.77 | LMNA (0.59) | LMNASLC22A6TSHRNFKB1PMP22 | |
| 4-(Hydroxyamino)Butanoic Acid SCHEMBL1655977 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2512411-A1 | COMPOSITION WITH ENHANCED HYDRATION ABILITY | L'Oréal (FR) | 2012-10-24 | — | — | EP | disclosed |
| WO-2011074127-A1 | COMPOSITION WITH ENHANCED HYDRATION ABILITY | L'OREAL (FR) | 2011-06-23 | — | — | WO | disclosed |
| US-RE32309-E | CORROSION RESISTANCE; SOFT SOLDER | SCM CORPORATION (US) | 1986-12-16 | — | — | US | disclosed |
| US-4557767-A | Fusible powdered metal paste | SCM CORPORATION (US) | 1985-12-10 | — | — | US | disclosed |