Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.47 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.47 |
| ▸ | RET | P07949 | 7/20 | 0.46 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2459991 | 0.91 | GPR119 (0.50) | GPR119MAPTALDH1A1LMNANR1H2 | |
| SCHEMBL16935349 | 0.85 | BACE1 (0.49) | GPR119MAPTALDH1A1LMNANR1H2 | |
| SCHEMBL3922803 | 0.84 | GPR119 (0.48) | GPR119MAPTALDH1A1LMNANR1H2 | |
| SCHEMBL20139774 | 0.83 | NR1H2 (0.48) | GPR119FFAR4MAPTALDH1A1LMNA | |
| SCHEMBL652792 | 0.83 | GRM5 (0.53) | GPR119MAPTALDH1A1LMNA | |
| SCHEMBL24984504 | 0.82 | GPR119 (0.45) | GPR119MAPTALDH1A1LMNANR1H2 | |
| SCHEMBL30163884 | 0.82 | GPR119 (0.45) | GPR119MAPTALDH1A1LMNANR1H2 | |
| SCHEMBL15114426 | 0.82 | MAPT (0.49) | MAPTALDH1A1LMNA | |
| SCHEMBL6269762 | 0.82 | GPR119 (0.57) | GPR119MAPTALDH1A1LMNANR1H2 | |
| SCHEMBL31474292 | 0.82 | GPR119 (0.57) | GPR119MAPTALDH1A1LMNANR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089493-A1 | PYRROLE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |