Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | EBP | Q15125 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | EPHB3 | P54753 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9421891 | 0.89 | MAPT (0.52) | MAPTHTTIDO1MEN1KMT2A | |
| SCHEMBL10734735 | 0.88 | TAAR1 (0.48) | TAAR1MAPTHTTIDO1MEN1 | |
| SCHEMBL7533377 | 0.81 | HTT (0.49) | MAPTHTTIDO1MEN1KMT2A | |
| SCHEMBL29415424 | 0.80 | MAPT (0.52) | TAAR1MAPTHTTIDO1MEN1 | |
| SCHEMBL328847 | 0.80 | MAPT (0.52) | TAAR1MAPTHTTIDO1MEN1 | |
| SCHEMBL11505439 | 0.78 | MAPT (0.47) | MAPTHTTIDO1MEN1KMT2A | |
| Ammonia Solution, Strong SCHEMBL8970822 | 0.78 | MAPT (0.50) | TAAR1MAPTHTTIDO1MEN1 | |
| SCHEMBL9615522 | 0.78 | KAT2B (0.53) | TAAR1MAPTHTTIDO1MEN1 | |
| SCHEMBL9069882 | 0.78 | NR4A2 (0.53) | MAPTHTTIDO1MEN1KMT2A | |
| SCHEMBL4162443 | 0.77 | MAPT (0.46) | MAPTHTTIDO1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4169919-A1 | PYRAZOLO[3,4-D]PYRIMIDINE-3-KETONE DERIVATIVE AS WEE-1 INHIBITOR | Wigen Biomedicine Technology (Shanghai) Co., Ltd. (CN) | 2023-04-26 | — | — | EP | disclosed |
| WO-2018089493-A1 | PYRROLE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |