Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23264381 | 0.82 | — | — | |
| SCHEMBL15573930 | 0.80 | KMT2A (0.40) | ADORA2AADORA2BGRM2ADORA1MAPT | |
| SCHEMBL33266 | 0.77 | ADORA2A (0.39) | ADORA2AADORA2BMAPTPOLBCRHR1 | |
| SCHEMBL20159662 | 0.74 | ADORA2A (0.37) | ADORA2AADORA2BPOLBCRHR1 | |
| SCHEMBL22981076 | 0.69 | — | — | |
| SCHEMBL31267051 | 0.65 | DGAT1 (0.37) | — | |
| SCHEMBL10284719 | 0.63 | NR1H3 (0.40) | MAPT | |
| SCHEMBL19286101 | 0.63 | SLC9A1 (0.38) | MAPT | |
| SCHEMBL5280505 | 0.61 | GRM2 (0.43) | ADORA2AADORA2BGRM2POLB | |
| SCHEMBL5280789 | 0.61 | GRM2 (0.43) | ADORA2AADORA2BGRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018087018-A1 | PHENOXYTRIAZOLES | F. HOFFMANN-LA ROCHE AG (CH) | 2018-05-17 | — | — | WO | disclosed |