Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 2/20 | 0.51 |
| ▸ | RPTOR | Q8N122 | 2/20 | 0.51 |
| ▸ | MLST8 | Q9BVC4 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 2/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | SMO | Q99835 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 4/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.36 |
| ▸ | HTR2C | P28335 | 3/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20158920 | 1.00 | MTOR (0.51) | MTORRPTORMLST8SMN1; SMN2FAAH | |
| SCHEMBL20159282 | 0.86 | MTOR (0.48) | MTORRPTORMLST8SMN1; SMN2MAPT | |
| SCHEMBL20159012 | 0.82 | MTOR (0.72) | MTORRPTORMLST8CHRM4PTGDR2 | |
| SCHEMBL20159122 | 0.81 | MTOR (0.42) | MTORRPTORMLST8FAAHCHRM4 | |
| SCHEMBL20140654 | 0.80 | MTOR (0.68) | MTORRPTORMLST8CHRM4PTGDR2 | |
| SCHEMBL20140657 | 0.80 | MTOR (0.68) | MTORRPTORMLST8CHRM4PTGDR2 | |
| SCHEMBL20141137 | 0.76 | MTOR (0.72) | MTORRPTORMLST8CHRM4CHRM2 | |
| SCHEMBL20141139 | 0.76 | MTOR (0.72) | MTORRPTORMLST8CHRM4CHRM2 | |
| SCHEMBL20159113 | 0.74 | MTOR (0.73) | MTORRPTORMLST8CHRM4MGLL | |
| SCHEMBL20139219 | 0.74 | MTOR (0.73) | MTORRPTORMLST8CHRM4MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089493-A1 | PYRROLE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |