Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FERMT2 | Q96AC1 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.34 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | CA3 | P07451 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA6 | P23280 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.32 |
| ▸ | CDK1 | P06493 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27888419 | 0.87 | FERMT2 (0.36) | FERMT2IDO1CDK1GLAGAA | |
| SCHEMBL11935799 | 0.82 | PRSS1 (0.36) | FERMT2IDO1CA12CA9CA3 | |
| SCHEMBL30045340 | 0.82 | IDO1 (0.36) | IDO1RAPGEF4SOS1CA12CA9 | |
| SCHEMBL5726787 | 0.78 | HPGD (0.49) | FERMT2IDO1RAPGEF4CDK1MAPT | |
| Hydrochloric Acid SCHEMBL4683451 | 0.76 | HPGD (0.47) | FERMT2IDO1RAPGEF4CDK1MAPT | |
| SCHEMBL18739206 | 0.75 | KCNH3 (0.39) | IDO1RAPGEF4CA12CA9CA1 | |
| SCHEMBL6231601 | 0.75 | TRPA1 (0.41) | IDO1RAPGEF4 | |
| SCHEMBL3005414 | 0.75 | TAAR1 (0.46) | FERMT2IDO1CDK1GAAMAPT | |
| SCHEMBL27888420 | 0.74 | HRH3 (0.35) | — | |
| Hydrochloric Acid SCHEMBL3027696 | 0.73 | TAAR1 (0.44) | FERMT2IDO1CDK1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089493-A1 | PYRROLE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |