Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD9 | Q9H8M2 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 3/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | SOS1 | Q07889 | 4/20 | 0.37 |
| ▸ | EGFR | P00533 | 2/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | AXL | P30530 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20142969 | 0.85 | BRD9 (0.41) | BRD9HTR2ASLC6A4KCNH2KDR | |
| SCHEMBL20143001 | 0.75 | HTR2A (0.38) | BRD9HTR2ASLC6A4KCNH2KDR | |
| SCHEMBL20138686 | 0.73 | SOS1 (0.36) | HTR2ASLC6A4KCNH2KDRSOS1 | |
| SCHEMBL20159238 | 0.73 | LMNA (0.38) | SLC6A4 | |
| SCHEMBL20138791 | 0.72 | KDR (0.41) | BRD9HTR2ASLC6A4KCNH2KDR | |
| SCHEMBL20142941 | 0.72 | HTR2A (0.37) | HTR2ASLC6A4KCNH2KDRSOS1 | |
| SCHEMBL20138713 | 0.72 | SOS1 (0.41) | HTR2ASLC6A4KCNH2KDRSOS1 | |
| SCHEMBL20142958 | 0.71 | EGFR (0.38) | HTR2ASLC6A4KCNH2KDRSOS1 | |
| SCHEMBL20142980 | 0.71 | HTR2A (0.36) | BRD9HTR2ASLC6A4KCNH2KDR | |
| SCHEMBL20154256 | 0.70 | SOS1 (0.36) | BRD9HTR2ASLC6A4KCNH2KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018087018-A1 | PHENOXYTRIAZOLES | F. HOFFMANN-LA ROCHE AG (CH) | 2018-05-17 | — | — | WO | disclosed |