Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20159440 | 0.83 | ROCK2 (0.51) | ROCK2NAMPT | |
| SCHEMBL20159536 | 0.82 | NAMPT (0.57) | ROCK2NAMPT | |
| SCHEMBL20159446 | 0.82 | NAMPT (0.60) | NAMPT | |
| SCHEMBL20159225 | 0.82 | ROCK2 (0.56) | ROCK2NAMPT | |
| SCHEMBL20142925 | 0.82 | ROCK2 (0.56) | ROCK2NAMPT | |
| SCHEMBL20159210 | 0.82 | ROCK2 (0.56) | ROCK2NAMPT | |
| SCHEMBL20159242 | 0.79 | NAMPT (0.54) | ROCK2NAMPT | |
| SCHEMBL20159453 | 0.79 | ROCK2 (0.54) | ROCK2NAMPT | |
| SCHEMBL20159151 | 0.79 | ROCK2 (0.55) | ROCK2NAMPT | |
| SCHEMBL20159221 | 0.78 | NAMPT (0.47) | ROCK2NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018086703-A1 | DIHYDROPYRIDAZINONES SUBSTITUTED WITH PHENYLUREAS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2018-05-17 | — | — | WO | disclosed |