Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 20/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20159433 | 0.87 | NAMPT (0.59) | NAMPT | |
| SCHEMBL20159466 | 0.87 | NAMPT (0.62) | NAMPT | |
| SCHEMBL20159249 | 0.85 | NAMPT (0.56) | NAMPT | |
| SCHEMBL20138899 | 0.83 | NAMPT (0.53) | NAMPT | |
| SCHEMBL20159409 | 0.83 | NAMPT (0.53) | NAMPT | |
| SCHEMBL20159573 | 0.82 | NAMPT (0.59) | NAMPT | |
| SCHEMBL20159429 | 0.82 | ROCK2 (0.56) | NAMPT | |
| SCHEMBL20138830 | 0.81 | ROCK2 (0.54) | NAMPT | |
| SCHEMBL20159444 | 0.81 | ROCK2 (0.54) | NAMPT | |
| SCHEMBL20139021 | 0.81 | ROCK2 (0.54) | NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018086703-A1 | DIHYDROPYRIDAZINONES SUBSTITUTED WITH PHENYLUREAS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2018-05-17 | — | — | WO | disclosed |