Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 3/20 | 0.49 |
| ▸ | GNAO1 | P09471 | 3/20 | 0.49 |
| ▸ | GNAI1 | P63096 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | NAAA | Q02083 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20159567 | 0.98 | GNAI3 (0.51) | GNAI3GNAO1GNAI1LMNAHSD17B10 | |
| SCHEMBL20159515 | 0.98 | GNAI3 (0.51) | GNAI3GNAO1GNAI1LMNAHSD17B10 | |
| SCHEMBL13817642 | 0.95 | LMNA (0.53) | GNAI3GNAO1GNAI1LMNAHSD17B10 | |
| SCHEMBL12039267 | 0.89 | HSD17B10 (0.52) | GNAI3GNAO1GNAI1LMNAHSD17B10 | |
| SCHEMBL9478831 | 0.87 | LMNA (0.48) | GNAI3GNAO1GNAI1LMNAHSD17B10 | |
| SCHEMBL21569626 | 0.84 | LMNA (0.46) | GNAI3GNAO1GNAI1LMNAHSD17B10 | |
| SCHEMBL21569642 | 0.83 | GNAI3 (0.45) | GNAI3GNAO1GNAI1LMNAHSD17B10 | |
| SCHEMBL21569685 | 0.83 | GNAI3 (0.45) | GNAI3GNAO1GNAI1LMNAHSD17B10 | |
| SCHEMBL24098152 | 0.83 | GNAI3 (0.68) | GNAI3GNAO1GNAI1LMNANAAA | |
| SCHEMBL14818931 | 0.83 | GNAI3 (0.52) | GNAI3GNAO1GNAI1LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089695-A1 | TOLL-LIKE RECEPTOR ANTAGONIST COMPOUNDS AND METHODS OF USE | DYNAVAX TECHNOLOGIES CORPORATION (US) | 2018-05-17 | — | — | WO | disclosed |