Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 3/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.38 |
| ▸ | LOX | P28300 | 1/20 | 0.37 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.37 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.35 |
| ▸ | SMARCA2 | P51531 | 2/20 | 0.35 |
| ▸ | SMARCA4 | P51532 | 2/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.32 |
| ▸ | GAK | O14976 | 1/20 | 0.32 |
| ▸ | ELOVL1 | Q9BW60 | 1/20 | 0.31 |
| ▸ | ACVR2A | P27037 | 1/20 | 0.31 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20159356 | 0.81 | CHRM4 (0.32) | LOXLOXL2CYP17A1CHRM4 | |
| SCHEMBL23504828 | 0.80 | — | — | |
| SCHEMBL20159687 | 0.76 | NR1H2 (0.41) | NR1H2NR1H3LOXLOXL2CYP17A1 | |
| SCHEMBL16685020 | 0.73 | CHRM4 (0.47) | NR1H2NR1H3LOXLOXL2CYP17A1 | |
| SCHEMBL19787604 | 0.72 | CHRM4 (0.43) | NR1H2NR1H3LOXLOXL2CYP17A1 | |
| Hydrochloric Acid SCHEMBL17077952 | 0.72 | CHRM4 (0.47) | NR1H2NR1H3LOXLOXL2CYP17A1 | |
| SCHEMBL21374488 | 0.71 | PSEN1 (0.45) | NR1H2NR1H3LOXLOXL2CYP17A1 | |
| SCHEMBL21069145 | 0.71 | PSEN1 (0.45) | NR1H2NR1H3LOXLOXL2CYP17A1 | |
| SCHEMBL21050448 | 0.71 | PSEN1 (0.45) | NR1H2NR1H3LOXLOXL2CYP17A1 | |
| SCHEMBL21050443 | 0.71 | PSEN1 (0.45) | NR1H2NR1H3LOXLOXL2CYP17A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018087018-A1 | PHENOXYTRIAZOLES | F. HOFFMANN-LA ROCHE AG (CH) | 2018-05-17 | — | — | WO | disclosed |