Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 6/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | BCR | P11274 | 1/20 | 0.36 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GPR3 | P46089 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16996394 | 0.99 | PGR (0.40) | PGRPDK2PDE4DABL1ABCB1 | |
| SCHEMBL15185753 | 0.96 | PGR (0.44) | PGRPDK2ABL1ABCB1BCR | |
| SCHEMBL16996396 | 0.95 | PDK2 (0.45) | PGRPDK2PDE4DABL1ABCB1 | |
| SCHEMBL10057765 | 0.93 | PGR (0.42) | PGRPDK2ABL1ABCB1BCR | |
| SCHEMBL17735813 | 0.92 | PDK2 (0.49) | PGRPDK2ABL1ABCB1BCR | |
| SCHEMBL11954910 | 0.92 | PDK2 (0.44) | PGRPDK2ABL1ABCB1BCR | |
| SCHEMBL10058152 | 0.92 | PDK2 (0.49) | PGRPDK2ABL1ABCB1BCR | |
| SCHEMBL10057800 | 0.92 | PDK2 (0.49) | PGRPDK2ABL1ABCB1BCR | |
| SCHEMBL29352894 | 0.92 | PDK2 (0.44) | PGRPDK2PDE4DABL1ABCB1 | |
| SCHEMBL20159380 | 0.92 | PDK2 (0.44) | PGRPDK2PDE4DABL1ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11563180-B2 | Spirobifluorene compound and perovskite solar cell comprising same | KOREA RESEARCH INSTITUTE OF CHECMICAL TECHNOLOGY (KR) | 2023-01-24 | — | — | US | disclosed |
| US-20190288207-A1 | SPIROBIFLUORENE COMPOUND AND PEROVSKITE SOLAR CELL COMPRISING SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2019-09-19 | — | — | US | disclosed |
| WO-2018088797-A1 | SPIROBIFLUORENE COMPOUND AND PEROVSKITE SOLAR CELL COMPRISING SAME | 한국화학연구원 | 2018-05-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11563180-B2 | Spirobifluorene compound and perovskite solar cell comprising same | SLC9B2, STOM, SLC46A1 | PGR 3108/4885PDK2 332/4885PDE4D 3883/4885 |
| US-20190288207-A1 | SPIROBIFLUORENE COMPOUND AND PEROVSKITE SOLAR CELL COMPRISING SAME | SLC9B2, STOM, SLC46A1 | PGR 3108/4885PDK2 332/4885PDE4D 3883/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.