Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 14/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | TDP2 | O95551 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20160255 | 0.88 | ATM (0.40) | BRD4MAPK14TDP2ATMMAOA | |
| SCHEMBL20160256 | 0.83 | BRD4 (0.38) | BRD4MAPK14TDP2ATMMAOA | |
| SCHEMBL20159920 | 0.80 | BRD4 (0.48) | BRD4MAPK14ATM | |
| SCHEMBL28475420 | 0.76 | BRD4 (0.47) | BRD4MAPK14 | |
| SCHEMBL20160288 | 0.75 | BRD4 (0.46) | BRD4MAPK14 | |
| SCHEMBL15549928 | 0.75 | BRD4 (0.53) | BRD4 | |
| SCHEMBL16654761 | 0.74 | BRD4 (0.53) | BRD4MAPK14 | |
| SCHEMBL21904906 | 0.74 | BRD4 (0.66) | BRD4MAPK14 | |
| SCHEMBL15553259 | 0.72 | BRD4 (0.71) | BRD4 | |
| SCHEMBL28831087 | 0.72 | BRD4 (0.46) | BRD4MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018086585-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF, AND APPLICATIONS THEREOF | 山东罗欣药业集团股份有限公司 | 2018-05-17 | — | — | WO | disclosed |