Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | CA3 | P07451 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA6 | P23280 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29475246 | 0.84 | KDM4E (0.38) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL22612669 | 0.82 | SMN1; SMN2 (0.50) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL3792833 | 0.82 | SMN1; SMN2 (0.50) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL20077205 | 0.82 | SMN1; SMN2 (0.37) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL20077212 | 0.82 | SMN1; SMN2 (0.37) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL1129578 | 0.82 | SMN1; SMN2 (0.50) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL21184224 | 0.82 | CA1 (0.32) | SMN1; SMN2CA1CA2CA14 | |
| SCHEMBL13603271 | 0.82 | CYP2C9 (0.34) | USP2L3MBTL1HDAC1HDAC2HDAC6 | |
| SCHEMBL12064029 | 0.81 | SMN1; SMN2 (0.45) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL12064041 | 0.81 | SMN1; SMN2 (0.45) | KDM4EMAPTTHRBALOX15NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020036904-A1 | NOVEL UREA-OXAZIRIDINES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-02-20 | — | — | WO | disclosed |
| WO-2018089951-A1 | REDOX-BASED REAGENTS FOR METHIONINE BIOCONJUGATION | REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-05-17 | — | — | WO | disclosed |