SCHEMBL1129578

SCHEMBL1129578

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nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ SMN1; SMN2 Q16637 2/20 0.50
▸ MAPT P10636 2/20 0.50
▸ KDM4E B2RXH2 1/20 0.50
▸ THRB P10828 1/20 0.50
▸ ALOX15 P16050 1/20 0.50
▸ NFKB1 P19838 1/20 0.50
▸ PTGS2 P35354 1/20 0.50
▸ THPO P40225 1/20 0.50
▸ RECQL P46063 1/20 0.50
▸ BLM P54132 1/20 0.50
▸ ALDH1A1 P00352 2/20 0.48
▸ GNPAT O15228 2/20 0.45
▸ FOLH1 Q04609 4/20 0.37
▸ NAALAD2 Q9Y3Q0 2/20 0.37
▸ RIMKLA Q8IXN7 1/20 0.37
▸ ACE P12821 1/20 0.34
▸ TGFBR1 P36897 1/20 0.34
▸ ALB P02768 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3792833 1.00 SMN1; SMN2 (0.50) SMN1; SMN2MAPTKDM4ETHRBALOX15
SCHEMBL22612669 1.00 SMN1; SMN2 (0.50) SMN1; SMN2MAPTKDM4ETHRBALOX15
SCHEMBL29475246 0.87 KDM4E (0.38) SMN1; SMN2MAPTKDM4ETHRBALOX15
SCHEMBL7608409 0.87 FOLH1 (0.38) SMN1; SMN2MAPTKDM4ETHRBALOX15
SCHEMBL30804200 0.85 SMN1; SMN2 (0.53) SMN1; SMN2MAPTKDM4ETHRBALOX15
SCHEMBL14611803 0.84 SIRT6 (0.41) SMN1; SMN2MAPTKDM4ETHRBALOX15
SCHEMBL12537172 0.82 ALDH1A1 (0.38) SMN1; SMN2MAPTKDM4ETHRBALOX15
SCHEMBL20160296 0.82 KDM4E (0.35) SMN1; SMN2MAPTKDM4ETHRBALOX15
SCHEMBL31167431 0.81 ACE (0.32) SMN1; SMN2MAPTKDM4ETHRBALOX15
SCHEMBL20077217 0.81 MAPT (0.53) SMN1; SMN2MAPTKDM4ETHRBALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10385015-B2 N-acylated methionine sulfoxides as food flavouring compounds GIVAUDAN S.A. (CH) 2019-08-20 — — US claimed
US-20170088512-A1 N-ACYLATED METHIONINE SULFOXIDES AS FOOD FLAVOURING COMPOUNDS GIVAUDAN S.A. (CH) 2017-03-30 — — US claimed
US-20260068916-A1 COMPOSITIONS COMPRISING A DIHYDROCHALCONE GIVAUDAN SA (CH) 2026-03-12 — — US disclosed
US-20260026536-A1 COMPOSITIONS COMPRISING A DIHYDROCHALCONE GIVAUDAN SA (CH) 2026-01-29 — — US disclosed
US-20250366502-A1 COMPOSITIONS CONTAINING BRAZZEIN GIVAUDAN SA (CH) 2025-12-04 — — US disclosed
US-20250289840-A1 RNA STABILIZING SUBSTANCES AND METHODS OF USE TEAM MEDICAL, LLC 2025-09-18 — — US disclosed
US-20250255332-A1 COMPOSITIONS COMPRISING AROMADENDRIN 3-ACETATE GIVAUDAN SA (CH) 2025-08-14 — — US disclosed
WO-2025093498-A1 COMPOSITIONS COMPRISING A MOGROSIDE GIVAUDAN SA (CH) 2025-05-08 — — WO disclosed
WO-2025093497-A1 COMPOSITIONS COMPRISING A DIHYDROCHALCONE GIVAUDAN SA (CH) 2025-05-08 — — WO disclosed
EP-4539677-A2 COMPOSITIONS CONTAINING BRAZZEIN Givaudan SA (CH) 2025-04-23 — — EP disclosed
CN-119768065-A Composition comprising amyrin 3-acetate 奇华顿股份有限公司 2025-04-04 — — CN disclosed
WO-2007112433-A2 COMPOSITIONS FOR PROMOTING HAIR GROWTH NOVUS INTERNATIONAL INC. (US) 2007-10-04 — — WO disclosed
US-20070072935-A1 Catalytic antioxidants and methods of use FLORIDA ATLANTIC UNIVERSITY (US) 2007-03-29 — — US disclosed
US-7129374-B2 Catalytic antioxidants and methods of use FLORIDA ATLANTIC UNIVERSITY (US) 2006-10-31 — — US disclosed
US-20040143016-A1 Catalytic antioxidants and methods of use FLORIDA ATLANTIC UNIVERSITY RESEARCH CORPORATION 2004-07-22 — — US disclosed
WO-2004047772-A2 CATALYTIC ANTIOXIDANTS AND METHODS OF USE FLORIDA ATLANTIC UNIVERSITY (US) 2004-06-10 — — WO disclosed
US-5952186-A QUANTITATIVE ANALYSIS OF METHIONINE SULFOXIDE IN PEPTIDE OR PROTEIN SAMPLE BY MIXING WITH METHIONINE REDUCTASE IN PRESENCE OF REDUCING AGENT HAVING SULFHYDRYL GROUP AND REPORTER TAG, DETECTING AMOUNT OF OXIDIZED REDUCING AGENT PROMEGA CORPORATION (US) 1999-09-14 — — US disclosed
EP-0900284-A1 NOVEL REAGENT, METHOD, AND KIT FOR THE QUANTITATION OF OXIDATION-REDUCTION PHENOMENA IN PROTEINS AND PEPTIDES PROMEGA CORPORATION (US) 1999-03-10 — — EP disclosed
WO-1997039141-A1 NOVEL REAGENT, METHOD, AND KIT FOR THE QUANTITATION OF OXIDATION-REDUCTION PHENOMENA IN PROTEINS AND PEPTIDES PROMEGA CORPORATION (US) 1997-10-23 — — WO disclosed
WO-1995014929-A1 DIMERIC OLIGOPEPTIDE MIXTURE SETS HOUGHTEN PHARMACEUTICALS, INC. (US) 1995-06-01 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10385015-B2 N-acylated methionine sulfoxides as food flavouring compounds MTR, MGMT, TAS1R1 SMN1; SMN2 249/4885MAPT 3192/4885KDM4E 1601/4885
US-20070072935-A1 Catalytic antioxidants and methods of use MSRB3, GSR, PRDX3 SMN1; SMN2 3367/4885MAPT 4130/4885KDM4E 1336/4885
US-20260026536-A1 COMPOSITIONS COMPRISING A DIHYDROCHALCONE TAS2R50, TAS2R5, TAS2R40 SMN1; SMN2 3119/4885MAPT 3336/4885KDM4E 132/4885
US-20040143016-A1 Catalytic antioxidants and methods of use MSRB3, GSR, PRDX3 SMN1; SMN2 3367/4885MAPT 4130/4885KDM4E 1336/4885
US-20250289840-A1 RNA STABILIZING SUBSTANCES AND METHODS OF USE SYNCRIP, SNRPA, RNASE1 SMN1; SMN2 261/4885MAPT 953/4885KDM4E 3958/4885
US-20170088512-A1 N-ACYLATED METHIONINE SULFOXIDES AS FOOD FLAVOURING COMPOUNDS MTR, MGMT, TAS1R1 SMN1; SMN2 249/4885MAPT 3192/4885KDM4E 1601/4885
US-20260068916-A1 COMPOSITIONS COMPRISING A DIHYDROCHALCONE TAS2R20, TAS2R50, TAS2R40 SMN1; SMN2 3683/4885MAPT 3410/4885KDM4E 80/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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