SCHEMBL22612669

SCHEMBL22612669

CC(=O)NC(CC[S+](C)[O-])C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ SMN1; SMN2 Q16637 2/20 0.50
▸ MAPT P10636 2/20 0.50
▸ KDM4E B2RXH2 1/20 0.50
▸ THRB P10828 1/20 0.50
▸ ALOX15 P16050 1/20 0.50
▸ NFKB1 P19838 1/20 0.50
▸ PTGS2 P35354 1/20 0.50
▸ THPO P40225 1/20 0.50
▸ RECQL P46063 1/20 0.50
▸ BLM P54132 1/20 0.50
▸ ALDH1A1 P00352 2/20 0.48
▸ GNPAT O15228 2/20 0.45
▸ FOLH1 Q04609 4/20 0.37
▸ NAALAD2 Q9Y3Q0 2/20 0.37
▸ RIMKLA Q8IXN7 1/20 0.37
▸ ACE P12821 1/20 0.34
▸ TGFBR1 P36897 1/20 0.34
▸ ALB P02768 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3792833 1.00 SMN1; SMN2 (0.50) SMN1; SMN2MAPTKDM4ETHRBALOX15
SCHEMBL1129578 1.00 SMN1; SMN2 (0.50) SMN1; SMN2MAPTKDM4ETHRBALOX15
SCHEMBL29475246 0.87 KDM4E (0.38) SMN1; SMN2MAPTKDM4ETHRBALOX15
SCHEMBL7608409 0.87 FOLH1 (0.38) SMN1; SMN2MAPTKDM4ETHRBALOX15
SCHEMBL30804200 0.85 SMN1; SMN2 (0.53) SMN1; SMN2MAPTKDM4ETHRBALOX15
SCHEMBL14611803 0.84 SIRT6 (0.41) SMN1; SMN2MAPTKDM4ETHRBALOX15
SCHEMBL12537172 0.82 ALDH1A1 (0.38) SMN1; SMN2MAPTKDM4ETHRBALOX15
SCHEMBL20160296 0.82 KDM4E (0.35) SMN1; SMN2MAPTKDM4ETHRBALOX15
SCHEMBL31167431 0.81 ACE (0.32) SMN1; SMN2MAPTKDM4ETHRBALOX15
SCHEMBL20077217 0.81 MAPT (0.53) SMN1; SMN2MAPTKDM4ETHRBALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4417061-A1 FOOD SUPPLEMENT FOR ANIMALS, PREPARATION METHOD THEREOF AND USE OF SAME Adibio, S.l. (ES) 2024-08-21 — — EP claimed
WO-2023062251-A1 FOOD SUPPLEMENT FOR ANIMALS, PREPARATION METHOD THEREOF AND USE OF SAME ADIBIO, S.L. (ES) 2023-04-20 — — WO claimed
CN-122081135-A Lactobacillus plantarum strain enriched in gamma-aminobutyric acid and application — 2026-05-26 — — CN disclosed
US-12584924-B2 Compositions and methods for diagnosing and treating chronic kidney disease SOCIETE DES PRODUITS NESTLE S.A. (CH) 2026-03-24 — — US disclosed
US-20260076944-A1 COMPOSITIONS AND METHODS FOR PROMOTING BRAIN HEALTH UNIV CALIFORNIA (US) 2026-03-19 — — US disclosed
US-20260022384-A1 ASPARAGINE SYNTHETASE INHIBITORS AND USES THEREOF OSPEDALE SAN RAFFAELE S.R.L. (IT) 2026-01-22 — — US disclosed
US-20250375505-A1 COMPOSITIONS AND METHODS FOR MODIFYING BILE ACIDS TO REGULATE LIPID AND STEROID METABOLISM UNIV CALIFORNIA (US) 2025-12-11 — — US disclosed
US-20250295713-A1 COMPOSITIONS AND METHODS FOR IMPROVING SKIN HEALTH AND FOR THE TREATMENT AND PREVENTION OF DISEASES, DISORDERS AND CONDITIONS ASSOCIATED WITH PATHOGENIC MICROBES DERMBIONT, INC. 2025-09-25 — — US disclosed
EP-4417061-A1 FOOD SUPPLEMENT FOR ANIMALS, PREPARATION METHOD THEREOF AND USE OF SAME Adibio, S.l. (ES) 2024-08-21 — — EP disclosed
US-12064459-B2 Compositions and methods for improving skin health and for the treatment and prevention of diseases, disorders and conditions associated with pathogenic microbes DERMBIONT, INC. (US) 2024-08-20 — — US disclosed
CN-118435054-A Compositions and methods for diagnosing and treating chronic kidney disease 雀巢产品有限公司 2024-08-02 — — CN disclosed
US-20210386802-A1 COMPOSITIONS AND METHODS FOR IMPROVING SKIN HEALTH AND FOR THE TREATMENT AND PREVENTION OF DISEASES, DISORDERS AND CONDITIONS ASSOCIATED WITH PATHOGENIC MICROBES DERMBIONT, INC. 2021-12-16 — — US disclosed
US-20210361725-A1 COMPOSITIONS AND METHODS FOR IMPROVING SKIN HEALTH AND FOR THE TREATMENT AND PREVENTION OF DISEASES, DISORDERS AND CONDITIONS ASSOCIATED WITH PATHOGENIC MICROBES DERMBIONT, INC. 2021-11-25 — — US disclosed
WO-2021202564-A1 COMPOSITIONS AND METHODS FOR CONTROLLING CELLULAR IDENTITY KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY (SA) 2021-10-07 — — WO disclosed
EP-3847257-A1 ASPARAGINE SYNTHETASE INHIBITORS AND USES THEREOF Ospedale San Raffaele S.r.l. (IT) 2021-07-14 — — EP disclosed
US-11040077-B2 Compositions and methods for improving skin health and for the treatment and prevention of diseases, disorders and conditions associated with pathogenic microbes DERMBIONT, INC. (US) 2021-06-22 — — US disclosed
WO-2021076999-A1 FECAL-DERIVED STERILE POSTBIOTIC COMPOSITION AND METHOD THEREFOR HUBBLE BIOSCIENCE INC. (US) 2021-04-22 — — WO disclosed
US-20210038654-A1 COMPOSITIONS FOR MODULATING GUT MICROFLORA POPULATIONS, ENHANCING DRUG POTENCY AND TREATING CANCER, AND METHODS FOR MAKING AND USING SAME PERSEPHONE BIOSCIENCES INC. 2021-02-11 — — US disclosed
US-20200345799-A1 COMPOSITIONS AND METHODS FOR IMPROVING SKIN HEALTH AND FOR THE TREATMENT AND PREVENTION OF DISEASES, DISORDERS AND CONDITIONS ASSOCIATED WITH PATHOGENIC MICROBES DERMBIONT, INC. 2020-11-05 — — US disclosed
CN-102112124-A Protection of normal cells UNIV FLORIDA ATLANTIC 2011-06-29 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250375505-A1 COMPOSITIONS AND METHODS FOR MODIFYING BILE ACIDS TO REGULATE LIPID AND STEROID METABOLISM CYP27A1, LIPC, CYP46A1 SMN1; SMN2 4332/4885MAPT 1772/4885KDM4E 3711/4885
US-20260076944-A1 COMPOSITIONS AND METHODS FOR PROMOTING BRAIN HEALTH IDO1, INMT, IDO2 SMN1; SMN2 1923/4885MAPT 1253/4885KDM4E 553/4885
US-12584924-B2 Compositions and methods for diagnosing and treating chronic kidney disease GLS, AADAT, FGF23 SMN1; SMN2 2156/4885MAPT 3150/4885KDM4E 124/4885
US-20260022384-A1 ASPARAGINE SYNTHETASE INHIBITORS AND USES THEREOF ASNS, AARS1, NARS1 SMN1; SMN2 3592/4885MAPT 2780/4885KDM4E 3487/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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