Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT6 | P42226 | 10/20 | 0.47 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.36 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24555967 | 0.86 | STAT6 (0.43) | STAT6CSNK1DKDM4EGAAALOX15 | |
| SCHEMBL22874060 | 0.82 | AURKA (0.43) | KDM4EGAASMN1; SMN2 | |
| SCHEMBL20161118 | 0.80 | CSNK1D (0.46) | STAT6CSNK1DKDM4EMAPTGAA | |
| SCHEMBL22213515 | 0.76 | LMNA (0.38) | KDM4EGAAALDH1A1SMN1; SMN2PTK2 | |
| SCHEMBL19240910 | 0.76 | AURKA (0.37) | STAT6KDM4EGAAALDH1A1 | |
| SCHEMBL17517364 | 0.76 | KCNH2 (0.53) | SMN1; SMN2 | |
| SCHEMBL19241027 | 0.75 | RPS6KB1 (0.37) | KDM4EALOX15ALDH1A1 | |
| SCHEMBL15987095 | 0.72 | LMNA (0.38) | KDM4EMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL19146434 | 0.72 | LMNA (0.35) | KDM4EMAPTALDH1A1SMN1; SMN2PTK2 | |
| SCHEMBL24555994 | 0.71 | GAA (0.35) | STAT6KDM4EMAPTGAAALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4233851-A1 | A SOLUBLE GUANYLAT CYCLASE ACTIVATOR FOR TREATING CHRONIC VASCULAR DYSFUNCTION | Charité - Universitätsmedizin Berlin (DE) | 2023-08-30 | — | — | EP | disclosed |
| WO-2018089330-A2 | SGC STIMULATORS | IRONWOOD PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |