Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 3/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | GCGR | P47871 | 2/20 | 0.39 |
| ▸ | GCG | P01275 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | FNTA | P49354 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20161208 | 0.82 | CA12 (0.47) | IDH1CA12CA1CA2CA9 | |
| SCHEMBL8145201 | 0.71 | SLC6A4 (0.56) | — | |
| SCHEMBL13185639 | 0.68 | MEN1 (0.54) | MAPTLMNAL3MBTL1MAPK1NLRP1 | |
| SCHEMBL20132434 | 0.68 | HKDC1 (0.58) | IDH1CA12CA1CA2CA9 | |
| SCHEMBL3782085 | 0.67 | IDO1 (0.44) | MAPTLMNAMAPK1NLRP1MEN1 | |
| SCHEMBL20132432 | 0.66 | HDAC1 (0.65) | IDH1GCGRGCGHDAC1HDAC8 | |
| SCHEMBL20236858 | 0.66 | MEN1 (0.55) | CA1CA2L3MBTL1ALDH1A1GCGR | |
| SCHEMBL20236349 | 0.66 | HKDC1 (0.52) | CA1CA2MAPTLMNAL3MBTL1 | |
| SCHEMBL12971594 | 0.66 | HIF1A (0.57) | CA1CA2MAPTL3MBTL1PKM | |
| SCHEMBL20132430 | 0.66 | HIF1A (0.63) | CA1CA2MAPTL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089651-A1 | PHENYL AND PYRIDINYL HYDROXAMIC ACIDS | ACETYLON PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |