Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | STAT3 | P40763 | 2/20 | 0.42 |
| ▸ | IDH1 | O75874 | 1/20 | 0.41 |
| ▸ | FNTA | P49354 | 1/20 | 0.40 |
| ▸ | FNTB | P49356 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20161206 | 0.82 | IDH1 (0.46) | CA12CA1CA2CA9MAPT | |
| SCHEMBL8145201 | 0.79 | SLC6A4 (0.56) | SLC6A4HTR2AKCNH2SLC6A2 | |
| SCHEMBL13185639 | 0.75 | MEN1 (0.54) | MAPTL3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL3782085 | 0.74 | IDO1 (0.44) | MAPTMEN1KMT2ASLC6A4HTR2A | |
| SCHEMBL11512030 | 0.72 | MEN1 (0.53) | CA12CA1CA2CA9MAPT | |
| SCHEMBL11510338 | 0.72 | MAPT (0.57) | CA12CA1CA2CA9MAPT | |
| SCHEMBL13754370 | 0.70 | GAA (0.46) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL13846533 | 0.68 | HTR2A (0.46) | HTR2A | |
| SCHEMBL13167601 | 0.68 | MEN1 (0.53) | MAPTL3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL855529 | 0.68 | MAPT (0.50) | MAPTL3MBTL1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089651-A1 | PHENYL AND PYRIDINYL HYDROXAMIC ACIDS | ACETYLON PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |