Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 2/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.34 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24467275 | 1.00 | ROCK2 (0.34) | ROCK2ROCK1CXCR4 | |
| SCHEMBL16455039 | 0.87 | — | — | |
| SCHEMBL14111108 | 0.87 | — | — | |
| SCHEMBL90066 | 0.87 | — | — | |
| Hydrochloric Acid SCHEMBL25346774 | 0.85 | KAT6A (0.31) | — | |
| Hydrochloric Acid SCHEMBL25346768 | 0.85 | KAT6A (0.31) | — | |
| SCHEMBL2914772 | 0.82 | NCF1 (0.39) | CXCR4 | |
| SCHEMBL2910055 | 0.82 | CXCR4 (0.35) | CXCR4 | |
| SCHEMBL2920006 | 0.80 | CXCR4 (0.31) | CXCR4 | |
| SCHEMBL2919967 | 0.79 | CHRNB4 (0.31) | CXCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023196278-A1 | ITK INHIBITORS FOR INCREASING TH1 CELL ACTIVITY | CORVUS PHARMACEUTICALS, INC. (US) | 2023-10-12 | — | — | WO | disclosed |
| WO-2018089261-A2 | COMPOUNDS AND METHODS FOR MODULATING INTERLEUKIN-2-INDUCIBLE T-CELL KINASE | CORVUS PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |