SCHEMBL20161464

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3712032	0.77	CYP1A2 (0.46)	TAAR1ALDH1A1CYP1A2CYP3A4CYP2D6
	SCHEMBL20161327	0.74	NPC1 (0.38)	TAAR1IDO1DPP4CYP3A4CYP2D6
	SCHEMBL3282116	0.72	DPP4 (0.66)	TAAR1IDO1DPP4CYP3A4CYP2D6
	SCHEMBL27490477	0.72	CYP1A2 (0.40)	CYP1A2GOT1
	SCHEMBL3281088	0.72	KCNA5 (0.47)	DPP4CYP3A4CYP2D6SLC6A2SLC6A4
	SCHEMBL3281177	0.71	DPP4 (0.47)	TAAR1IDO1DPP4CYP3A4CYP2D6
	SCHEMBL12706272	0.71	TAAR1 (0.47)	TAAR1ALDH1A1TSHRMAPK1IDO1
	SCHEMBL12495185	0.71	CYP1A2 (0.42)	CYP1A2GOT1
	SCHEMBL8267903	0.70	TAAR1 (0.50)	TAAR1ALDH1A1IDO1DPP4CYP3A4
	SCHEMBL3674139	0.69	TAAR1 (0.54)	TAAR1ALDH1A1IDO1DPP4CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.