Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ALPG | P10696 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.39 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24326253 | 0.82 | MAPT (0.52) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL31545915 | 0.76 | MAPT (0.55) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL2897385 | 0.76 | MAPT (0.55) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL2905084 | 0.76 | MAPT (0.57) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL8645091 | 0.76 | NPC1 (0.45) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL2905085 | 0.76 | MAPT (0.57) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL8654854 | 0.74 | KAT2B (0.66) | ALDH1A1MAPTMEN1KMT2AGAA | |
| SCHEMBL8647822 | 0.73 | KAT2B (0.60) | ALDH1A1MAPTMEN1KMT2AGAA | |
| Hydrochloric Acid SCHEMBL8645147 | 0.73 | KAT2B (0.67) | ALDH1A1MAPTMEN1KMT2AGAA | |
| SCHEMBL20390494 | 0.73 | ALDH1A1 (0.60) | ALDH1A1MAPTMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089261-A2 | COMPOUNDS AND METHODS FOR MODULATING INTERLEUKIN-2-INDUCIBLE T-CELL KINASE | CORVUS PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |