Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 11/20 | 0.41 |
| ▸ | JAK3 | P52333 | 9/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TXK | P42681 | 8/20 | 0.36 |
| ▸ | ITK | Q08881 | 8/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24467200 | 0.88 | L3MBTL3 (0.34) | BTKTXKITK | |
| SCHEMBL27089747 | 0.84 | KMT2A (0.56) | BTKJAK3MEN1KMT2ATXK | |
| SCHEMBL24467259 | 0.83 | MEN1 (0.38) | BTKJAK3MEN1KMT2ATXK | |
| SCHEMBL20139704 | 0.78 | BTK (0.43) | BTKJAK3MEN1KMT2ATXK | |
| SCHEMBL20161948 | 0.72 | GAA (0.42) | MEN1KMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL24467293 | 0.68 | TAAR1 (0.47) | MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL27089746 | 0.66 | KMT2A (0.52) | BTKJAK3MEN1KMT2ATXK | |
| SCHEMBL18830589 | 0.64 | HTR2A (0.37) | MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL20139588 | 0.62 | JAK3 (0.40) | BTKJAK3MEN1KMT2ATXK | |
| SCHEMBL31213431 | 0.62 | JAK3 (0.40) | BTKJAK3MEN1KMT2ATXK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089261-A2 | COMPOUNDS AND METHODS FOR MODULATING INTERLEUKIN-2-INDUCIBLE T-CELL KINASE | CORVUS PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |