Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | TRAP1 | Q12931 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18830589 | 0.85 | HTR2A (0.37) | TAAR1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL18928321 | 0.81 | MAPT (0.45) | TAAR1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL13048381 | 0.81 | NPSR1 (0.43) | ALDH1A1NPSR1 | |
| SCHEMBL20161948 | 0.80 | GAA (0.42) | MAPTSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL12466982 | 0.77 | MAPT (0.53) | TAAR1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL6556289 | 0.76 | CYP3A4 (0.53) | TAAR1SMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL4396090 | 0.76 | TAAR1 (0.79) | TAAR1MAPTSMN1; SMN2 | |
| SCHEMBL13678722 | 0.76 | APLNR (0.39) | MAPTSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL19932825 | 0.76 | TAAR1 (0.52) | TAAR1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL22381403 | 0.75 | TAAR1 (0.55) | TAAR1MAPTSMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3534899-B1 | COMPOUNDS AND METHODS FOR MODULATING INTERLEUKIN-2-INDUCIBLE T-CELL KINASE | CORVUS PHARMACEUTICALS INC (US) | 2022-06-01 | — | — | EP | disclosed |