Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.76 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.76 |
| ▸ | LMNA | P02545 | 3/20 | 0.66 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.66 |
| ▸ | GALR3 | O60755 | 1/20 | 0.66 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1738957 | 1.00 | KDM4E (0.76) | KDM4EL3MBTL1LMNAHIF1AGALR3 | |
| SCHEMBL2011932 | 1.00 | KDM4E (0.76) | KDM4EL3MBTL1LMNAHIF1AGALR3 | |
| Aniline SCHEMBL28119003 | 0.91 | KDM4E (0.63) | KDM4EL3MBTL1LMNAHIF1AGALR3 | |
| Aniline SCHEMBL27981889 | 0.89 | KDM4E (0.61) | KDM4EL3MBTL1LMNAHIF1AGALR3 | |
| SCHEMBL4408535 | 0.87 | KDM4E (1.00) | KDM4EL3MBTL1LMNAAOC3ALDH1A1 | |
| SCHEMBL7532494 | 0.87 | KDM4E (1.00) | KDM4EL3MBTL1LMNAAOC3ALDH1A1 | |
| Benzene SCHEMBL27731714 | 0.85 | KDM4E (0.55) | KDM4EL3MBTL1LMNAHIF1AGALR3 | |
| Benzene SCHEMBL27711181 | 0.85 | KDM4E (0.55) | KDM4EL3MBTL1LMNAHIF1AGALR3 | |
| Benzene SCHEMBL27711276 | 0.85 | KDM4E (0.55) | KDM4EL3MBTL1LMNAHIF1AGALR3 | |
| Benzene SCHEMBL27711202 | 0.85 | KDM4E (0.55) | KDM4EL3MBTL1LMNAHIF1AGALR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4173673-A1 | IMIDAZOLONE DERIVATIVES AS INHIBITORS OF PROTEIN KINASES IN PARTICULAR DYRK1A, CLK1 AND/OR CLK4 | Perha Pharmaceuticals (FR) | 2023-05-03 | — | — | EP | disclosed |
| EP-2513069-B1 | ANTIFUNGAL COMPOUNDS | UNIV LEUVEN KATH (BE) | 2014-10-15 | — | — | EP | disclosed |
| EP-2513069-A1 | ANTIFUNGAL COMPOUNDS | Katholieke Universiteit Leuven (BE) | 2012-10-24 | — | — | EP | disclosed |
| US-20120252801-A1 | ANTIFUNGAL COMPOUNDS | KATHOLIEKE UNIVERSITEIT LEUVEN, K.U.LEUVEN R&D (BE) | 2012-10-04 | — | — | US | disclosed |
| US-8097708-B2 | 10a-Azalide compound | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2012-01-17 | — | — | US | disclosed |
| WO-2011072345-A1 | ANTIFUNGAL COMPOUNDS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2011-06-23 | — | — | WO | disclosed |
| US-20090281292-A1 | 10a-Azalide Compound | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2009-11-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090281292-A1 | 10a-Azalide Compound | IL17A, AZI2, HDAC9 | KDM4E 128/4885L3MBTL1 2853/4885LMNA 1467/4885 |
| US-20120252801-A1 | ANTIFUNGAL COMPOUNDS | ERG28, DPM1, CYP51A1 | KDM4E 3907/4885L3MBTL1 4233/4885LMNA 3928/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.