Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 1.00 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 1.00 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.68 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.56 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7532494 | 1.00 | KDM4E (1.00) | KDM4EL3MBTL1AOC3LMNAALDH1A1 | |
| SCHEMBL12186411 | 0.89 | KDM4E (0.80) | KDM4EL3MBTL1AOC3LMNAALDH1A1 | |
| SCHEMBL7114926 | 0.89 | KDM4E (0.80) | KDM4EL3MBTL1AOC3LMNAALDH1A1 | |
| Acetic Acid SCHEMBL8948216 | 0.89 | KDM4E (0.80) | KDM4EL3MBTL1AOC3LMNAALDH1A1 | |
| SCHEMBL7288245 | 0.89 | KDM4E (0.79) | KDM4EL3MBTL1AOC3LMNAALDH1A1 | |
| SCHEMBL8976776 | 0.88 | KDM4E (0.77) | KDM4EL3MBTL1AOC3LMNAALDH1A1 | |
| SCHEMBL9061582 | 0.88 | KDM4E (0.77) | KDM4EL3MBTL1AOC3LMNAALDH1A1 | |
| SCHEMBL2011932 | 0.87 | KDM4E (0.76) | KDM4EL3MBTL1AOC3LMNAALDH1A1 | |
| SCHEMBL1738957 | 0.87 | KDM4E (0.76) | KDM4EL3MBTL1AOC3LMNAALDH1A1 | |
| SCHEMBL2016180 | 0.87 | KDM4E (0.76) | KDM4EL3MBTL1AOC3LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7635776-B2 | Ligands and complex compounds containing the same | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2009-12-22 | — | — | US | disclosed |
| US-20060111572-A1 | Ligands and complex compounds containing the same | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2006-05-25 | — | — | US | disclosed |
| EP-1591439-A1 | LIGANDS AND COMPLEX COMPOUNDS CONTAINING THE SAME | Takasago International Corporation (JP) | 2005-11-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060111572-A1 | Ligands and complex compounds containing the same | NR0B2, NR4A1, NR0B1 | KDM4E 2545/4885L3MBTL1 3985/4885AOC3 1000/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.