Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SLC11A2 | P49281 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16962085 | 0.77 | CYP3A4 (0.36) | PRSS1PRSS2PRSS3CYP3A4TSHR | |
| SCHEMBL24633579 | 0.74 | TSHR (0.33) | TSHR | |
| SCHEMBL13652487 | 0.74 | — | — | |
| SCHEMBL24063666 | 0.74 | — | — | |
| SCHEMBL13756309 | 0.72 | CYP3A4 (0.33) | PRSS1PRSS2PRSS3CYP3A4TSHR | |
| SCHEMBL3203530 | 0.72 | SMN1; SMN2 (0.48) | CYP3A4TSHRBCHEACHEMAOB | |
| SCHEMBL23011778 | 0.72 | MEN1 (0.46) | PRSS1PRSS2PRSS3CYP3A4TSHR | |
| SCHEMBL17085840 | 0.72 | TDP1 (0.46) | MAPT | |
| SCHEMBL24633558 | 0.71 | TSHR (0.33) | TSHR | |
| SCHEMBL22753250 | 0.71 | CYP2A6 (0.44) | PRSS1PRSS2PRSS3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089261-A2 | COMPOUNDS AND METHODS FOR MODULATING INTERLEUKIN-2-INDUCIBLE T-CELL KINASE | CORVUS PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |