Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 5/20 | 0.37 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.35 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4403107 | 0.94 | SMN1; SMN2 (0.52) | SMN1; SMN2TSHRALDH1A1KDM4EHTT | |
| SCHEMBL14436800 | 0.92 | SMN1; SMN2 (0.56) | SMN1; SMN2TSHRALDH1A1KDM4EHTT | |
| SCHEMBL26115100 | 0.82 | KDM4E (0.44) | SMN1; SMN2TSHRALDH1A1KDM4EHTT | |
| SCHEMBL3285509 | 0.82 | ALDH1A1 (0.48) | SMN1; SMN2TSHRALDH1A1KDM4EHTT | |
| SCHEMBL30597489 | 0.82 | KDM4E (0.44) | SMN1; SMN2TSHRALDH1A1KDM4EHTT | |
| SCHEMBL29657461 | 0.82 | ALDH1A1 (0.48) | SMN1; SMN2TSHRALDH1A1KDM4EHTT | |
| SCHEMBL12198248 | 0.80 | SMN1; SMN2 (0.41) | SMN1; SMN2TSHRALDH1A1KDM4EMAPT | |
| SCHEMBL2791334 | 0.80 | GPR27 (0.42) | SMN1; SMN2TSHRALDH1A1KDM4EMAPT | |
| SCHEMBL19161558 | 0.80 | TSHR (0.50) | SMN1; SMN2TSHRALDH1A1KDM4EHTT | |
| SCHEMBL14924942 | 0.80 | SMN1; SMN2 (0.46) | SMN1; SMN2TSHRALDH1A1KDM4EMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200251661-A1 | HETEROCYCLIC COMPOUND AND ORGANIC ELECTRONIC DEVICE COMPRISING SAME | LG CHEM, LTD. (KR) | 2020-08-06 | — | — | US | disclosed |
| US-20150322002-A1 | N-SUBSTITUTED BENZAMIDES AND METHODS OF USE THEREOF | GENENTECH, INC. (US) | 2015-11-12 | — | — | US | disclosed |
| EP-2135671-B1 | Catalyst and method for producing carboxylic acid and/or carboxylic anhydride in the presence of the catalyst | MITSUBISHI GAS CHEMICAL CO (JP) | 2015-03-04 | — | — | EP | disclosed |
| US-8357625-B2 | Catalyst and method for producing carboxylic acid and/or carboxylic anhydride in the presence of the catalyst | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2013-01-22 | — | — | US | disclosed |
| US-8299055-B2 | 8-substituted isoquinoline derivative and the use thereof | ASAHI KASEI PHARMA CORPORATION (JP) | 2012-10-30 | — | — | US | disclosed |
| EP-1701938-B1 | 1,3-DIPHENYLPROP-2-EN-1-ONE DERIVATIVE COMPOUNDS, PREPARATION METHOD THEREOF AND USES OF SAME | GENFIT (FR) | 2012-07-25 | — | — | EP | disclosed |
| EP-1701938-B1 | 1,3-DIPHENYLPROP-2-EN-1-ONE DERIVATIVE COMPOUNDS, PREPARATION METHOD THEREOF AND USES OF SAME | GENFIT (FR) | 2012-07-25 | — | — | EP | disclosed |
| WO-2011143343-A1 | INTEGRATION-FREE HUMAN INDUCED PLURIPOTENT STEM CELLS FROM BLOOD | IPIERIAN, INC. (US) | 2011-11-17 | — | — | WO | disclosed |
| US-7964724-B2 | Chiral cis-imidazolines | HOFFMANN-LA ROCHE INC. (US) | 2011-06-21 | — | — | US | disclosed |
| US-20100261701-A1 | 8-Substituted isoquinoline derivative and the use thereof | ASAHI KASEI PHARMA CORPORATION (JP) | 2010-10-14 | — | — | US | disclosed |
| US-20080058412-A1 | 1,3-Diphenylprop-2-En-1-One Derivative Compounds, Preparation Method Thereof and Uses of Same | GENFIT (FR) | 2008-03-06 | — | — | US | disclosed |
| EP-1701938-A1 | 1,3-DIPHENYLPROP-2-EN-1-ONE DERIVATIVE COMPOUNDS, PREPARATION METHOD THEREOF AND USES OF SAME | Genfit (FR) | 2006-09-20 | — | — | EP | disclosed |
| US-7019166-B2 | Method for the production of 2,4,5-trimethylphenyl acetic acid | BAYER CROPSCIENCE AG (DE) | 2006-03-28 | — | — | US | disclosed |
| US-20050182274-A1 | Method for the production of 2,4,5-trimethylphenyl acetic acid | BAYER CROPSCIENCE AG (DE) | 2005-08-18 | — | — | US | disclosed |
| WO-2005073184-A1 | 1,3-DIPHENYLPROP-2-EN-1-ONE DERIVATIVE COMPOUNDS, PREPARATION METHOD THEREOF AND USES OF SAME | GENFIT (FR) | 2005-08-11 | — | — | WO | disclosed |
| EP-1494987-A1 | METHOD FOR THE PRODUCTION OF 2,4,5-TRIMETHYLPHENYL ACETIC ACID | Bayer CropScience AG (DE) | 2005-01-12 | — | — | EP | disclosed |
| WO-2003084914-A1 | METHOD FOR THE PRODUCTION OF 2,4,5-TRIMETHYLPHENYL ACETIC ACID | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2003-10-16 | — | — | WO | disclosed |
| US-4184874-A | Photosensitive composition containing chelate compound | FUJI PHOTO FILM CO., LTD. (JP) | 1980-01-22 | — | — | US | disclosed |
| US-3975373-A | CYCLOPENTANONE HELVETICOSIDE | JOHANN A. WULFING FABRIK PHARMAZEUTISCHER PRAPARATE (DT) | 1976-08-17 | — | — | US | disclosed |
| US-3951946-A | Cardioglycoside derivatives of the strophanthidin type, a process for their manufacture and medicinal preparations containing these compounds | JOHANN A. WULFING FABRIK PHARMAZEUTISCHER PRAPARATE (DT) | 1976-04-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150322002-A1 | N-SUBSTITUTED BENZAMIDES AND METHODS OF USE THEREOF | BRIX1, SNRPD2, RDX | SMN1; SMN2 1855/4885TSHR 635/4885ALDH1A1 1364/4885 |
| US-20080058412-A1 | 1,3-Diphenylprop-2-En-1-One Derivative Compounds, Preparation Method Thereof and Uses of Same | TYR, DHPS, DDT | SMN1; SMN2 3337/4885TSHR 4505/4885ALDH1A1 7/4885 |
| US-20050182274-A1 | Method for the production of 2,4,5-trimethylphenyl acetic acid | CA6, DDC, HACL2 | SMN1; SMN2 4449/4885TSHR 2279/4885ALDH1A1 234/4885 |
| US-20200251661-A1 | HETEROCYCLIC COMPOUND AND ORGANIC ELECTRONIC DEVICE COMPRISING SAME | ODC1, OR10J3, CYP1A1 | SMN1; SMN2 2582/4885TSHR 3861/4885ALDH1A1 82/4885 |
| US-20100261701-A1 | 8-Substituted isoquinoline derivative and the use thereof | RELA, NFKBIA, NFKB2 | SMN1; SMN2 3014/4885TSHR 4176/4885ALDH1A1 1380/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.