SCHEMBL24633558

SCHEMBL24633558

Bc1cc(C)c(C(C)=N)cc1F

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.33
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25687069 0.81 TSHR (0.36) TSHRALDH1A1
SCHEMBL24633579 0.74 TSHR (0.33) TSHRALDH1A1
SCHEMBL18929647 0.73 ACHE (0.33)
SCHEMBL5364899 0.71 GPR3 (0.32)
SCHEMBL20161881 0.71 PRSS1 (0.39) TSHR
SCHEMBL10290142 0.70 CYP3A4 (0.42) TSHRALDH1A1
SCHEMBL24900933 0.69 ALDH1A1 (0.33) TSHRALDH1A1
SCHEMBL17085841 0.67 CES2 (0.39) ALDH1A1
SCHEMBL24800954 0.67
SCHEMBL8860024 0.64 ALDH1A1 (0.43) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022240830-A1 C-LINKED INHIBITORS OF ENL/AF9 YEATS BRIDGE MEDICINES (US) 2022-11-17 WO disclosed