Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.47 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.40 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.40 |
| ▸ | TNNC1 | P63316 | 5/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.40 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.40 |
| ▸ | GPR183 | P32249 | 1/20 | 0.40 |
| ▸ | CERS2 | Q96G23 | 1/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.40 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | BID | P55957 | 3/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.38 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.38 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.38 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL11614736 | 1.00 | LIPG (0.47) | LIPGNR1H2NR1H3CYSLTR2CYSLTR1 | |
| Bromide SCHEMBL20163268 | 1.00 | LIPG (0.47) | LIPGNR1H2NR1H3CYSLTR2CYSLTR1 | |
| SCHEMBL2530765 | 0.98 | LIPG (0.49) | LIPGNR1H2NR1H3CYSLTR2CYSLTR1 | |
| SCHEMBL1537240 | 0.98 | LIPG (0.49) | LIPGNR1H2NR1H3CYSLTR2CYSLTR1 | |
| SCHEMBL8592575 | 0.98 | LIPG (0.49) | LIPGNR1H2NR1H3CYSLTR2CYSLTR1 | |
| Hydrochloric Acid SCHEMBL2059992 | 0.97 | LIPG (0.47) | LIPGNR1H2NR1H3CYSLTR2CYSLTR1 | |
| Hydrochloric Acid SCHEMBL15811749 | 0.97 | LIPG (0.47) | LIPGNR1H2NR1H3CYSLTR2CYSLTR1 | |
| Hydrochloric Acid SCHEMBL29286909 | 0.97 | LIPG (0.47) | LIPGNR1H2NR1H3CYSLTR2CYSLTR1 | |
| Hydrochloric Acid SCHEMBL8591558 | 0.97 | LIPG (0.47) | LIPGNR1H2NR1H3CYSLTR2CYSLTR1 | |
| Hydrochloric Acid SCHEMBL3387556 | 0.97 | LIPG (0.47) | LIPGNR1H2NR1H3CYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10870224-B2 | Method of manufacturing antireflection film | FUJIFILM CORPORATION (JP) | 2020-12-22 | — | — | US | disclosed |
| US-20190011604-A1 | LAMINATE, METHOD OF MANUFACTURING LAMINATE, AND METHOD OF MANUFACTURING ANTIREFLECTION FILM | FUJIFILM CORPORATION (JP) | 2019-01-10 | — | — | US | disclosed |
| US-20180141245-A1 | METHOD OF MANUFACTURING ANTIREFLECTION FILM | FUJIFILM CORPORATION (JP) | 2018-05-24 | — | — | US | disclosed |