Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 known ✓ | P21453 | 2/20 | 0.42 |
| ▸ | S1PR4 known ✓ | O95977 | 1/20 | 0.40 |
| ▸ | S1PR3 known ✓ | Q99500 | 1/20 | 0.40 |
| ▸ | S1PR5 known ✓ | Q9H228 | 1/20 | 0.40 |
| ▸ | KCNH2 known ✓ | Q12809 | 1/20 | 0.39 |
| ▸ | PPARG known ✓ | P37231 | 1/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.47 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.40 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.40 |
| ▸ | TNNC1 | P63316 | 5/20 | 0.40 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.40 |
| ▸ | GPR183 | P32249 | 1/20 | 0.40 |
| ▸ | CERS2 | Q96G23 | 1/20 | 0.40 |
| ▸ | BID | P55957 | 3/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.38 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.38 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.38 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2059992 | 1.00 | LIPG (0.47) | LIPGS1PR1NR1H2NR1H3CYSLTR2 | |
| Hydrochloric Acid SCHEMBL29286909 | 1.00 | LIPG (0.47) | LIPGS1PR1NR1H2NR1H3CYSLTR2 | |
| Hydrochloric Acid SCHEMBL8591558 | 1.00 | LIPG (0.47) | LIPGS1PR1NR1H2NR1H3CYSLTR2 | |
| Hydrochloric Acid SCHEMBL15811749 | 1.00 | LIPG (0.47) | LIPGS1PR1NR1H2NR1H3CYSLTR2 | |
| SCHEMBL8592575 | 0.98 | LIPG (0.49) | LIPGS1PR1NR1H2NR1H3CYSLTR2 | |
| Hydrochloric Acid SCHEMBL28845901 | 0.98 | LIPG (0.45) | LIPGS1PR1NR1H2NR1H3CYSLTR2 | |
| SCHEMBL1537240 | 0.98 | LIPG (0.49) | LIPGS1PR1NR1H2NR1H3CYSLTR2 | |
| SCHEMBL2530765 | 0.98 | LIPG (0.49) | LIPGS1PR1NR1H2NR1H3CYSLTR2 | |
| Bromide SCHEMBL20163268 | 0.97 | LIPG (0.47) | LIPGS1PR1NR1H2NR1H3CYSLTR2 | |
| Bromide SCHEMBL11614736 | 0.97 | LIPG (0.47) | LIPGS1PR1NR1H2NR1H3CYSLTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115894291-A | Preparation method of alpha-cyhalothrin | 江苏优嘉植物保护有限公司 | 2023-04-04 | — | — | CN | claimed |
| US-5658671-A | ARTICLE COATED WITH COMPOSITION COMPRISING FLUOROELASTOMER, QUATERNARY AMMONIUM OR PHOSPHONIUM ACCELERATOR, POLYOL, ACID ACCEPTOR, OIL-SOLUBLE CHELATING AGENT, ORGANIC SOLVENT | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1997-08-19 | — | — | US | claimed |
| US-5451625-A | FOR USE IN THE PREPARATION OF AUTOMOTIVE GASKETS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-09-19 | — | — | US | claimed |
| EP-0574319-A1 | Fluoroelastomer coating composition | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1993-12-15 | — | — | EP | claimed |
| US-11988809-B2 | Laminate, antireflection product, and manufacturing method thereof | FUJIFILM CORPORATION (JP) | 2024-05-21 | — | — | US | disclosed |
| US-20240085784-A1 | ORGANIC EL DISPLAY DEVICE | TOYO INK SC HOLDINGS CO., LTD. (JP) | 2024-03-14 | — | — | US | disclosed |
| EP-4166712-A1 | METHOD FOR PRODUCING COAGULATED MATERIAL | DIC Corporation (JP) | 2023-04-19 | — | — | EP | disclosed |
| CN-115894291-A | Preparation method of alpha-cyhalothrin | 江苏优嘉植物保护有限公司 | 2023-04-04 | — | — | CN | disclosed |
| US-11567238-B2 | Laminate, antireflection product having three-dimensional curved surface, and method of manufacturing antireflection product | FUJIFILM CORPORATION (JP) | 2023-01-31 | — | — | US | disclosed |
| WO-2022224779-A1 | ORGANIC EL DISPLAY DEVICE | 東洋インキＳＣホールディングス株式会社 | 2022-10-27 | — | — | WO | disclosed |
| CN-109564384-B | Photosensitive coloring composition and color filter | 东洋油墨SC控股株式会社 | 2022-09-20 | — | — | CN | disclosed |
| CN-111825559-B | Quaternary ammonium salt ionic liquid, synthesis method and application thereof as metal corrosion inhibitor | 河南大学 | 2022-07-08 | — | — | CN | disclosed |
| US-5658671-A | ARTICLE COATED WITH COMPOSITION COMPRISING FLUOROELASTOMER, QUATERNARY AMMONIUM OR PHOSPHONIUM ACCELERATOR, POLYOL, ACID ACCEPTOR, OIL-SOLUBLE CHELATING AGENT, ORGANIC SOLVENT | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1997-08-19 | — | — | US | disclosed |
| EP-0670868-B1 | FLUORORUBBER COATING COMPOSITION | MINNESOTA MINING & MFG (US) | 1997-01-22 | — | — | EP | disclosed |
| US-5451625-A | FOR USE IN THE PREPARATION OF AUTOMOTIVE GASKETS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-09-19 | — | — | US | disclosed |
| EP-0670868-A1 | FLUORORUBBER COATING COMPOSITION. | MINNESOTA MINING & MFG (US) | 1995-09-13 | — | — | EP | disclosed |
| US-5407774-A | Charge control agent and positively chargeable toner for developing electrostatic images | ORIENT CHEMICAL INDUSTRIES, LTD. (JP) | 1995-04-18 | — | — | US | disclosed |
| WO-1994012580-A1 | FLUORORUBBER COATING COMPOSITION | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1994-06-09 | — | — | WO | disclosed |
| EP-0579207-A1 | Charge control agent and positively chargeable toner for developing electrostatic images | ORIENT CHEMICAL INDUSTRIES, LTD. (JP) | 1994-01-19 | — | — | EP | disclosed |
| EP-0574319-A1 | Fluoroelastomer coating composition | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1993-12-15 | — | — | EP | disclosed |