Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18227082 | 0.87 | MAPT (0.43) | KDM4ELMNAMAPTMAPK1HTT | |
| SCHEMBL9937249 | 0.85 | MAPT (0.53) | KDM4ELMNAMAPTMAPK1HTT | |
| SCHEMBL20164019 | 0.81 | RXFP1 (0.50) | KDM4ELMNAMAPTMAPK1HTT | |
| SCHEMBL9937458 | 0.81 | RXFP1 (0.62) | MAPTHTTMEN1KMT2ARXFP1 | |
| SCHEMBL15452568 | 0.75 | RXFP1 (0.67) | MAPTHTTMEN1KMT2ARXFP1 | |
| SCHEMBL18227081 | 0.73 | MAPT (0.53) | KDM4ELMNAMAPTMAPK1HTT | |
| SCHEMBL29882847 | 0.71 | MEN1 (0.45) | KDM4ELMNAMAPTMAPK1HTT | |
| SCHEMBL142911 | 0.68 | HTT (0.59) | KDM4ELMNAMAPTMAPK1HTT | |
| SCHEMBL15452564 | 0.67 | RXFP1 (0.73) | KDM4EMAPTMEN1KMT2ARXFP1 | |
| SCHEMBL28222179 | 0.66 | KMT2A (0.51) | KDM4ELMNAMAPTMAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180140585-A1 | BIOMOLECULES INVOLVED IN ALZHEIMER'S DISEASE | ELECTROPHORETICS LIMITED (GB) | 2018-05-24 | — | — | US | disclosed |