Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18256274 | 0.91 | POLB (0.57) | POLBL3MBTL1ALDH1A1LMNAHSD17B10 | |
| SCHEMBL20164214 | 0.88 | POLB (0.52) | POLBL3MBTL1ALDH1A1LMNAHSD17B10 | |
| SCHEMBL18256275 | 0.88 | CYP4F2 (0.42) | POLBL3MBTL1ALDH1A1LMNAHSD17B10 | |
| SCHEMBL18249393 | 0.82 | CYP4F2 (0.43) | L3MBTL1ALDH1A1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL18249396 | 0.82 | LMNA (0.49) | POLBL3MBTL1ALDH1A1LMNAHSD17B10 | |
| SCHEMBL20164232 | 0.81 | LMNA (0.45) | POLBL3MBTL1ALDH1A1LMNAHSD17B10 | |
| SCHEMBL18249456 | 0.80 | HDAC1 (0.48) | POLBL3MBTL1ALDH1A1LMNAHSD17B10 | |
| SCHEMBL18249450 | 0.79 | LMNA (0.44) | POLBL3MBTL1ALDH1A1LMNAHSD17B10 | |
| SCHEMBL18489650 | 0.79 | CYP4F2 (0.51) | POLBL3MBTL1ALDH1A1LMNAKMT2A | |
| SCHEMBL20164260 | 0.78 | LMNA (0.46) | POLBL3MBTL1ALDH1A1LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3298048-B1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA SRL (IT) | 2019-07-03 | — | — | EP | disclosed |
| US-10221256-B2 | Catalyst components for the polymerization of olefins | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2019-03-05 | — | — | US | disclosed |
| US-20180142044-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2018-05-24 | — | — | US | disclosed |