Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | SCN1A | P35498 | 2/20 | 0.41 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.41 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18256274 | 0.89 | POLB (0.57) | LMNAPOLBALDH1A1HSD17B10L3MBTL1 | |
| SCHEMBL18249450 | 0.88 | LMNA (0.44) | LMNAPOLBALDH1A1HSD17B10L3MBTL1 | |
| SCHEMBL20164234 | 0.88 | USP2 (0.44) | ALDH1A1KMT2ASMN1; SMN2GAATP53 | |
| SCHEMBL20164211 | 0.86 | ELANE (0.40) | LMNAALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL18249468 | 0.86 | LMNA (0.42) | LMNAPOLBALDH1A1HSD17B10L3MBTL1 | |
| SCHEMBL18256275 | 0.85 | CYP4F2 (0.42) | LMNAPOLBALDH1A1HSD17B10L3MBTL1 | |
| SCHEMBL15542727 | 0.85 | LMNA (0.44) | LMNAPOLBALDH1A1SCN1ASCN2A | |
| SCHEMBL20164214 | 0.82 | POLB (0.52) | LMNAPOLBALDH1A1HSD17B10L3MBTL1 | |
| SCHEMBL20164201 | 0.81 | POLB (0.51) | LMNAPOLBALDH1A1HSD17B10L3MBTL1 | |
| SCHEMBL18249424 | 0.80 | L3MBTL1 (0.41) | LMNAPOLBALDH1A1HSD17B10L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3298048-B1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA SRL (IT) | 2019-07-03 | — | — | EP | disclosed |
| US-10221256-B2 | Catalyst components for the polymerization of olefins | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2019-03-05 | — | — | US | disclosed |
| US-20180142044-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2018-05-24 | — | — | US | disclosed |