Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | AHR | P35869 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.38 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20164282 | 0.86 | LMNA (0.46) | TP53LMNAL3MBTL1KMT2AMAPT | |
| SCHEMBL20164213 | 0.80 | KMT2A (0.41) | TP53LMNAKMT2AMAPTNPC1 | |
| SCHEMBL20164258 | 0.80 | KMT2A (0.43) | TP53LMNAL3MBTL1KMT2AMAPT | |
| SCHEMBL18249398 | 0.77 | GAA (0.40) | TP53LMNAL3MBTL1KMT2AMAPT | |
| SCHEMBL20164254 | 0.76 | LMNA (0.47) | TP53LMNAL3MBTL1KMT2AMAPT | |
| SCHEMBL20164233 | 0.76 | KMT2A (0.49) | TP53LMNAL3MBTL1KMT2AMAPT | |
| SCHEMBL18249395 | 0.76 | GAA (0.40) | TP53LMNAKMT2AMAPTNPC1 | |
| SCHEMBL18249413 | 0.75 | KMT2A (0.46) | LMNAKMT2AMAPTNPC1RAB9A | |
| SCHEMBL20164247 | 0.75 | KMT2A (0.45) | TP53LMNAKMT2AMAPTNPC1 | |
| SCHEMBL18249482 | 0.74 | TP53 (0.47) | TP53LMNAKMT2AMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3298048-B1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA SRL (IT) | 2019-07-03 | — | — | EP | disclosed |
| US-10221256-B2 | Catalyst components for the polymerization of olefins | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2019-03-05 | — | — | US | disclosed |
| US-20180142044-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2018-05-24 | — | — | US | disclosed |