Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | AHR | P35869 | 1/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20164221 | 0.90 | HPGD (0.52) | KMT2ANPC1RAB9ALMNACYP2C9 | |
| SCHEMBL18249405 | 0.85 | KMT2A (0.67) | KMT2ANPC1RAB9ALMNANR1I2 | |
| SCHEMBL20164252 | 0.83 | KMT2A (0.51) | KMT2ANPC1RAB9ALMNANR1I2 | |
| SCHEMBL20164278 | 0.80 | KMT2A (0.55) | KMT2ANPC1RAB9ALMNANR1I2 | |
| SCHEMBL20164203 | 0.80 | ALDH1A1 (0.55) | KMT2ANPC1RAB9ALMNANR1I2 | |
| SCHEMBL3829756 | 0.77 | ALDH1A1 (0.60) | KMT2ANPC1RAB9ALMNACYP2C9 | |
| SCHEMBL18249416 | 0.76 | ALDH1A1 (0.56) | KMT2ANPC1RAB9ALMNANR1I2 | |
| SCHEMBL20164255 | 0.76 | TP53 (0.43) | KMT2ANPC1RAB9ALMNANR1I2 | |
| SCHEMBL18249387 | 0.75 | ALDH1A1 (0.52) | KMT2ANPC1RAB9ALMNANR1I2 | |
| SCHEMBL28876649 | 0.75 | NLRP3 (0.49) | KMT2ANPC1RAB9ALMNANR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3298048-B1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA SRL (IT) | 2019-07-03 | — | — | EP | disclosed |
| US-10221256-B2 | Catalyst components for the polymerization of olefins | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2019-03-05 | — | — | US | disclosed |
| US-20180142044-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2018-05-24 | — | — | US | disclosed |