Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18249380 | 0.89 | KMT2A (0.46) | SMN1; SMN2ALDH1A1CYP1A2CYP2C19CYP2C9 | |
| SCHEMBL28876723 | 0.89 | SMN1; SMN2 (0.40) | SMN1; SMN2ALDH1A1CYP1A2CYP2C19CYP2C9 | |
| SCHEMBL20164249 | 0.88 | ALDH1A1 (0.46) | SMN1; SMN2ALDH1A1CYP1A2CYP2C19CYP2C9 | |
| SCHEMBL18249474 | 0.87 | SMN1; SMN2 (0.52) | SMN1; SMN2ALDH1A1CYP1A2CYP2C19CYP2C9 | |
| SCHEMBL20164293 | 0.87 | SMN1; SMN2 (0.41) | SMN1; SMN2ALDH1A1CYP1A2CYP2C19CYP2C9 | |
| SCHEMBL20164278 | 0.84 | KMT2A (0.55) | SMN1; SMN2ALDH1A1CYP1A2CYP2C19CYP2C9 | |
| SCHEMBL18249416 | 0.81 | ALDH1A1 (0.56) | SMN1; SMN2ALDH1A1CYP1A2CYP2C19CYP2C9 | |
| SCHEMBL20164259 | 0.81 | SMN1; SMN2 (0.48) | SMN1; SMN2ALDH1A1CYP1A2CYP2C19CYP2C9 | |
| SCHEMBL18249441 | 0.80 | SMN1; SMN2 (0.47) | SMN1; SMN2ALDH1A1CYP1A2CYP2C19CYP2C9 | |
| SCHEMBL15233901 | 0.80 | POLB (0.38) | SMN1; SMN2CYP1A2CYP2C19CYP2C9MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3298048-B1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA SRL (IT) | 2019-07-03 | — | — | EP | disclosed |
| US-10221256-B2 | Catalyst components for the polymerization of olefins | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2019-03-05 | — | — | US | disclosed |
| US-20180142044-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2018-05-24 | — | — | US | disclosed |