Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18249409 | 0.88 | SMN1; SMN2 (0.49) | ALDH1A1LMNATP53SMN1; SMN2TRPV1 | |
| SCHEMBL20164265 | 0.88 | SMN1; SMN2 (0.44) | ALDH1A1LMNASMN1; SMN2TRPV1MAPT | |
| SCHEMBL18249380 | 0.88 | KMT2A (0.46) | ALDH1A1LMNASMN1; SMN2MAPTKMT2A | |
| SCHEMBL18249488 | 0.86 | ALDH1A1 (0.54) | ALDH1A1LMNATP53SMN1; SMN2TRPV1 | |
| SCHEMBL20164237 | 0.85 | KMT2A (0.47) | ALDH1A1LMNATP53SMN1; SMN2TRPV1 | |
| SCHEMBL15535214 | 0.80 | LMNA (0.42) | ALDH1A1LMNATP53SMN1; SMN2TRPV1 | |
| SCHEMBL20164293 | 0.80 | SMN1; SMN2 (0.41) | ALDH1A1LMNASMN1; SMN2MAPTKDM4E | |
| SCHEMBL16236470 | 0.79 | LMNA (0.42) | ALDH1A1LMNATP53SMN1; SMN2TRPV1 | |
| SCHEMBL25921373 | 0.79 | KMT2A (0.48) | ALDH1A1LMNATP53SMN1; SMN2MAPT | |
| SCHEMBL15535057 | 0.78 | LMNA (0.41) | ALDH1A1LMNATP53SMN1; SMN2TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3298048-B1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA SRL (IT) | 2019-07-03 | — | — | EP | disclosed |
| US-10221256-B2 | Catalyst components for the polymerization of olefins | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2019-03-05 | — | — | US | disclosed |
| US-20180142044-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2018-05-24 | — | — | US | disclosed |