Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | SCNN1A | P37088 | 4/20 | 0.36 |
| ▸ | DRD5 | P21918 | 1/20 | 0.36 |
| ▸ | SCNN1B | P51168 | 1/20 | 0.36 |
| ▸ | SCNN1G | P51170 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL2024368 | 0.99 | ALDH1A1 (0.36) | ALDH1A1KDM4EHPGDHSD17B10GAA | |
| SCHEMBL12635739 | 0.92 | ALDH1A1 (0.36) | ALDH1A1KDM4EHPGDHSD17B10GAA | |
| SCHEMBL12636678 | 0.91 | ALDH1A1 (0.35) | ALDH1A1KDM4EHPGDHSD17B10GAA | |
| SCHEMBL12635726 | 0.91 | APOBEC3A (0.39) | ALDH1A1KDM4EHPGDHSD17B10GAA | |
| Bromide SCHEMBL2053994 | 0.91 | ALDH1A1 (0.35) | ALDH1A1KDM4EHPGDHSD17B10GAA | |
| SCHEMBL12635761 | 0.91 | APAF1 (0.35) | ALDH1A1KDM4EHPGDHSD17B10GAA | |
| Bromide SCHEMBL2049875 | 0.90 | APOBEC3A (0.39) | ALDH1A1KDM4EHPGDHSD17B10GAA | |
| SCHEMBL12635737 | 0.89 | APAF1 (0.41) | ALDH1A1KDM4EHPGDHSD17B10GAA | |
| SCHEMBL12636679 | 0.89 | ALDH1A1 (0.35) | ALDH1A1KDM4EHPGDHSD17B10GAA | |
| SCHEMBL12636337 | 0.88 | ADORA2A (0.37) | ALDH1A1KDM4EHPGDHSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011079087-A1 | ENAC BLOCKERS | GLAXO GROUP LIMITED (GB) | 2011-06-30 | — | — | WO | claimed |
| WO-2011079087-A1 | ENAC BLOCKERS | GLAXO GROUP LIMITED (GB) | 2011-06-30 | — | — | WO | disclosed |